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Tg(Cnp-EGFP*)1Qrlu
Transgene Detail
Summary
Symbol: Tg(Cnp-EGFP*)1Qrlu
Name: transgene insertion 1, Q Richard Lu
MGI ID: MGI:5584296
Synonyms: CNP-mEGFP
Transgene: Tg(Cnp-EGFP*)1Qrlu  Location: unknown  
Alliance: Tg(Cnp-EGFP*)1Qrlu page
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene was designed with a membrane-anchored green fluorescent protein (mEGFP), which carries a Ras membrane localization (CAAX) sequence in the carboxy terminus of EGFP, driven by a 3.9-kb 2',3'-cyclic nucleotide 3' phosphodiesterase (Cnp) promoter, followed by a human beta-globin polyadenylation site. Five lines were generated that displayed similar levels of expression. This is a representative record for all lines. (J:213410)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:213410 Deng Y, et al., Direct visualization of membrane architecture of myelinating cells in transgenic mice expressing membrane-anchored EGFP. Genesis. 2014 Apr;52(4):341-9
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory