Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Neurod1-cre/ERT2)M1Fcal
Name:	transgene insertion M1, Federico Calegari
MGI ID:	MGI:5582823
Synonyms:	Neurod1-CreERT2
Transgene:	Tg(Neurod1-cre/ERT2)M1Fcal  Location: unknown
Alliance:	Tg(Neurod1-cre/ERT2)M1Fcal page

Strain of Origin:

C57BL/6JOlaHsd

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Neurod1-cre/ERT2)M1Fcal expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Neurod1 (MGI:1339708)   Mutation details: Bacterial artificial chromosome (BAC) library (Source BioScience) was used to obtain a 160 kb BAC (BMQ-305H2) containing the entire mouse Neurod1 gene. This BAC was modified to replace the coding region with a creERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand-binding domain) followed by a frt-flanked neomycin (neo) selection cassette. Four lines were generated: L (low expression), M1 (intermediate expression), M2, H (high expression). This is a representative record for all lines. Transgene expression patterns are consistent with endogenous gene expression. (J:213056)

Activity:	Tissue activity of this recombinase allele
Driver:	Neurod1 (mouse) Summary of all recombinase alleles driven by Neurod1. Comparative matrix view of recombinase activities Alliance mouse Neurod1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:213056 Aprea J, et al., Generation and characterization of Neurod1-CreER(T2) mouse lines for the study of embryonic and adult neurogenesis. Genesis. 2014 Oct;52(10):870-8
All:	3 reference(s)