Tg(CMV-cat,-Rhoa)4-19Koba
Transgene Detail
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| Symbol: |
Tg(CMV-cat,-Rhoa)4-19Koba |
| Name: |
transgene insertion 4-19, Kazuto Kobayashi |
| MGI ID: |
MGI:5578314 |
| Synonyms: |
CAT-RhoA DN/4-19 |
| Transgene: |
Tg(CMV-cat,-Rhoa)4-19Koba Location: unknown
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| Alliance: |
Tg(CMV-cat,-Rhoa)4-19Koba page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CMV-cat,-Rhoa)4-19Koba expresses
1 gene
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Mutation details: A 0.9 kb DNA fragment containing the cytomegalovirus early gene promoter was fused to the rabbit beta-globin second intron and chloramphenicol acetyltransferase (CAT) gene cassette connected to a polyadenylation signal, both ends of which were flanked by loxP sites. This was then followed by a 0.6 kb DNA fragment encoding a dominant-negative mutant for RhoA and a second polyadenylation signal.
(J:100207)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:100207 Kobayashi K, et al., Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8 |
| All: |
1 reference(s) |
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Analysis Tools
