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Gene Expression Data
Assay Details
Assay
Reference: J:167833 Yu S, et al., The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling. Dev Dyn. 2011 Feb;240(2):384-93
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5576572
Gene symbol: Smad1
Gene name: SMAD family member 1
Antibody: anti-Phospho-Smad1/5/9
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: This antibody recognizes the phosphorylated form of the protein.
Results
Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: heart Present Regionally restricted 6A Expression is in semilunar valves.

Specimen 6B: embryonic day 12.5; Ackr3tm1.1Twb/Ackr3tm1.1Twb (more )
Structure Level Pattern Image Note
TS20: heart Present Regionally restricted 6B The number of expressing cells is about 1.5-fold higher in mutant semilunar valves than in wild-type valves.

Specimen 6C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: heart valve Present Regionally restricted 6C Expression is in semilunar valves.

Specimen 6D: embryonic day 14.0; Ackr3tm1.1Twb/Ackr3tm1.1Twb (more )
Structure Level Pattern Image Note
TS22: heart valve Present Regionally restricted 6D The number of expressing cells is about 1.5-fold higher in mutant semilunar valves than in wild-type valves.

Specimen not shown E11.5 WT: embryonic day 11.5 (more )
Note: These data are reported in a graph illustrating the % of positive cells.
Structure Level Pattern Image Note
TS19: heart Present Regionally restricted Expression is in semilunar valves.

Specimen not shown E11.5 -/-: embryonic day 11.5; Ackr3tm1.1Twb/Ackr3tm1.1Twb (more )
Note: These data are reported in a graph illustrating the % of positive cells.
Structure Level Pattern Image Note
TS19: heart Present Regionally restricted The number of expressing cells is about 1.5-fold higher in mutant semilunar valves than in wild-type valves.

Specimen not shown E15.5 WT: embryonic day 15.5 (more )
Note: These data are reported in a graph illustrating the % of positive cells.
Structure Level Pattern Image Note
TS23: heart valve Present Regionally restricted Expression is in semilunar valves.

Specimen not shown E15.5 -/-: embryonic day 15.5; Ackr3tm1.1Twb/Ackr3tm1.1Twb (more )
Note: These data are reported in a graph illustrating the % of positive cells.
Structure Level Pattern Image Note
TS23: heart valve Present Regionally restricted The number of expressing cells is about 1.5-fold higher in mutant semilunar valves than in wild-type valves.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory