Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Sod1m1H
Name:	superoxide dismutase 1, soluble; mutation 1, Harwell
MGI ID:	MGI:5575771
Synonyms:	Sod1D83G
Gene:	Sod1  Location: Chr16:90017650-90023221 bp, + strand  Genetic Position: Chr16, 51.56 cM, cytoband B5-C3
Alliance:	Sod1m1H page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced an A to G transition in exon 3 that results in an aspartic acid to glycine missense mutation (D83G). Dismutase activity of the mutant protein is severely reduced compared to the wild-type protein. (J:169366, J:219360)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Sod1 Mutation:	37 strains or lines available

Original:	J:169366 MouseBookTM, Information obtained from MouseBookTM, Medical Research Council Mammalian Genetics Unit, Harwell, UK. Unpublished. 2005-2013;
All:	2 reference(s)