Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Piezo2tm1.1(cre)Apat
Name:	piezo-type mechanosensitive ion channel component 2; targeted mutation 1.1, Ardem Patapoutian
MGI ID:	MGI:5574478
Synonyms:	Piezo2-EGFP-IRES-Cre, Piezo2GFP
Gene:	Piezo2  Location: Chr18:63143284-63520254 bp, - strand  Genetic Position: Chr18, 35.95 cM, cytoband D3
Alliance:	Piezo2tm1.1(cre)Apat page

Germline Transmission:	Earliest citation of germline transmission: J:211312
Parent Cell Line:	C2 (Nagy) (ES Cell)
Strain of Origin:	C57BL/6NTac

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Piezo2tm1.1(cre)Apat expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Piezo2 (MGI:1918781)   Mutation details: An EGFP-IRES-cre cassette followed by an FRT-flanked neomycin resistance selection cassette and loxP site were inserted at the end of exon 54. Flp-mediated recombination removed the selection cassette. (J:211312) Inheritance:    Not Specified

Activity:	Tissue activity of this recombinase allele
Driver:	Piezo2 (mouse) Summary of all recombinase alleles driven by Piezo2. Comparative matrix view of recombinase activities Alliance mouse Piezo2 gene page

In Mice Carrying this Mutation:

14 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Piezo2 Mutation:	123 strains or lines available

Original:	J:211312 Woo SH, et al., Piezo2 is required for Merkel-cell mechanotransduction. Nature. 2014 May 29;509(7502):622-6
All:	23 reference(s)