Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Diaph3tm1.1Sna
Name:	diaphanous related formin 3; targeted mutation 1.1, Shuh Narumiya
MGI ID:	MGI:5574347
Gene:	Diaph3  Location: Chr14:86892803-87378671 bp, - strand  Genetic Position: Chr14, 43.95 cM, cytoband D3
Alliance:	Diaph3tm1.1Sna page

Germline Transmission:	Earliest citation of germline transmission: J:205519
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: One loxP site was inserted upstream of exon1 and a floxed neomycin resistance cassette was inserted downstream. Exon 1 was subsequently removed by cre excision. (J:205519)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Diaph3 Mutation:	88 strains or lines available

Original:	J:205519 Watanabe S, et al., Loss of a Rho-regulated actin nucleator, mDia2, impairs cytokinesis during mouse fetal erythropoiesis. Cell Rep. 2013 Nov 27;5(4):926-32
All:	1 reference(s)