About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:161205 Moreno-Bravo JA, et al., Dynamic expression patterns of Nkx6.1 and Nkx6.2 in the developing mes-diencephalic basal plate. Dev Dyn. 2010 Jul;239(7):2094-101
Assay type: RNA in situ
MGI Accession ID: MGI:5573141
Gene symbol: Nkx6-1
Gene name: NK6 homeobox 1
Probe: Nkx6-1 probe5
Probe preparation: Antisense RNA
Results
Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted 1E Expression is as a longitudinal stripe.
TS15: future midbrain Present Regionally restricted 1E Expression is as a longitudinal stripe.
Specimen 1F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present 1F
TS17: midbrain Present 1F
Specimen 1G: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Weak 1G
TS17: midbrain Weak 1G
Specimen 1H: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present 1H
TS17: midbrain Present 1H
TS17: midbrain-hindbrain junction Absent 1H
Specimen 1M: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future midbrain Present 1M
Specimen 1N: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 1N Expression is in the basal plate with a few expressing cells in the alar plate.
Specimen 1K: embryonic day 9.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946).
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 1K Expression is in the basal plate.
Specimen 1O: embryonic day 9.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946).
Structure Level Pattern Image Note
TS15: future midbrain Present Regionally restricted 1O Expression is in the basal plate.
Specimen 1P: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 1P Expression is in an alar and in a basal domain. The alar domain elongates parallel to the isthmus.
TS19: diencephalon Present Regionally restricted 1P Expression is in the basal area.
Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: midbrain ventricular layer Present Regionally restricted 2B Expression is in two ventricular domains in the alar and basal plates.
TS19: midbrain mantle layer Present Regionally restricted 2B Expression is in a group of positive cells in the mantle zone of the mesencephalic basal plate.
Specimen 2D: embryonic day 11.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946); blue - Pou4f1 (assay MGI:5573142).
Structure Level Pattern Image Note
TS19: midbrain Present Regionally restricted 2D Expression is in the basal plate.
Specimen 2F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2F Expression is as a broad longitudinal band in the basal plate.
TS19: midbrain mantle layer Present Regionally restricted 2F Expression is as a broad longitudinal band in the basal plate.
TS19: midbrain ventricular layer Present Regionally restricted 2F Expression is as a broad longitudinal band in the basal plate.
Specimen 2H: embryonic day 11.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946); blue - Pou4f1 (assay MGI:5573142).
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 2H Expression is as a broad longitudinal band in the basal plate.
TS19: midbrain Present Regionally restricted 2H Expression is as a broad longitudinal band in the basal plate.
Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain ventricular layer Present Regionally restricted 3B Expression is at the surface.
TS20: midbrain mantle layer Present Regionally restricted 3B Expression is as a longitudinal band.
Specimen 3D: embryonic day 12.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946); blue - Pou4f1 (assay MGI:5573142).
Structure Level Pattern Image Note
TS20: midbrain ventricular layer Present Regionally restricted 3D Expression is at the surface.
TS20: midbrain mantle layer Present Regionally restricted 3D Expression is as a longitudinal band.
Specimen 3F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: midbrain ventricular layer Present Regionally restricted 3F Expression is at the surface.
TS20: diencephalon Present Regionally restricted 3F Expression is as a longitudinal band.
TS20: midbrain mantle layer Present Regionally restricted 3F Expression is as a longitudinal band.
Specimen 3H: embryonic day 12.5 (more )
Note: Color-coded overlays of adjacent sections. Colors: red - Nkx6-1; green - Nkx6-2 (assay MGI:5572946); blue - Pou4f1 (assay MGI:5573142).
Structure Level Pattern Image Note
TS20: midbrain ventricular layer Present Regionally restricted 3H Expression is at the surface.
TS20: diencephalon Present Regionally restricted 3H Expression is as a longitudinal band.
TS20: midbrain mantle layer Present Regionally restricted 3H Expression is as a longitudinal band.
Specimen 4E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Present Regionally restricted 4E
TS23: midbrain Present Regionally restricted 4E
Specimen 4F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: midbrain Present Regionally restricted 4F
Specimen 4G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 4G Expression is in the oculomotor nucleus, interpeduncular nucleus, in diverse parts of the reticular formation and in trigeminal and facial motor cranial nuclei.
Specimen 4H: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 4H Expression is in the oculomotor nucleus, interpeduncular nucleus, in diverse parts of the reticular formation and in trigeminal and facial motor cranial nuclei.
Specimen not shown p7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: midbrain Present Regionally restricted
Specimen not shown p15: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: midbrain Present Regionally restricted
Specimen not shown adult: postnatal adult (more )
Structure Level Pattern Image Note
TS28: midbrain Present Regionally restricted
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory