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Gene Expression Data
Assay Details
Assay
Reference: J:52029 Koutsourakis M, et al., The transcription factor GATA6 is essential for early extraembryonic development. (Errata: v. 126(9):U4). Development. 1999 Feb;126(4):723-32
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5569656
Gene symbol: Gata6
Gene name: GATA binding protein 6
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 3.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present Non-Uniform 2A
TS4: extraembryonic component Present Single cells 2A Expression is present in cells lining the blastocoel cavity.
Specimen 2B: embryonic day 3.5; Gata6tm1Gsv/Gata6tm1Gsv (more )
Structure Level Pattern Image Note
TS4: inner cell mass Present Non-Uniform 2B
TS4: extraembryonic component Present Single cells 2B Expression is present in cells lining the blastocoel cavity.
Specimen 2C left: embryonic day 7.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS10: parietal endoderm Present 2C left Expression is present in the parietal endoderm cells of the Reichert's membrane.
TS10: embryo Absent 2C left
Specimen 2C right: embryonic day 7.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS10: parietal endoderm Present 2C right Expression is present in the parietal endoderm cells of the Reichert's membrane.
Specimen 2D: embryonic day 7.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS10: Reichert's membrane Present Single cells 2D Expression is present in the parietal endoderm cells of the Reichert's membrane.
TS10: parietal endoderm Present Single cells 2D Expression is present in the parietal endoderm cells of the Reichert's membrane.
TS10: embryo ectoderm Absent 2D
TS10: embryo endoderm Absent 2D
TS10: embryo mesoderm Absent 2D
Specimen 3A: embryonic day 7.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present 3A
Specimen 3B: embryonic day 8.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present 3B
Specimen 3C: embryonic day 8.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS12: cardiogenic plate Present 3C
Specimen 3D: embryonic day 8.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Present 3D
Specimen 3E: embryonic day 8.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS12: heart Present 3E
Specimen 3F: embryonic day 8.0; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS12: primitive heart tube Present 3F
Specimen 3G: embryonic day 8.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS13: heart Present 3G
TS13: sinus venosus left horn Present 3G This is the site of primary expression.
TS13: sinus venosus right horn Present 3G This is the site of primary expression.
TS13: foregut diverticulum Present 3G
Specimen 3H: embryonic day 8.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS13: heart Present Regionally restricted 3H Expression is present in the myocardium and pericardium; it is not evident in the endocardium.
TS13: cardiac muscle tissue Present 3H
TS13: endocardial tube Absent 3H
Specimen 4A: embryonic day 9.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS15: heart Strong Non-Uniform 4A Expression is particularly seen in the inflow and outflow tracts.
TS15: outflow tract Strong 4A
TS15: foregut Very strong 4A
TS15: hindgut Very strong 4A
TS15: midgut Present 4A
Specimen 4B: embryonic day 9.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS15: heart Strong Non-Uniform 4B Expression is particularly seen in the inflow and outflow tracts.
TS15: outflow tract Strong 4B
Specimen 4C: embryonic day 9.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS15: cardiac muscle tissue Present 4C
TS15: endocardial lining Absent 4C
Specimen 5A: embryonic day 4.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS5: inner cell mass Present Regionally restricted 5A Expression is restricted to a population of cells on the blastocoelic surface of the inner cell mass adjacent to the trophectoderm.
Specimen 5B: embryonic day 5.5; Gata6tm1Gsv/Gata6tm1Gsv (more )
Structure Level Pattern Image Note
TS6: blastocyst-stage conceptus Present Single cells 5B Expression is only seen in a few cells in a subset of embryos.
Specimen 5C: embryonic day 5.5; Gata6tm1Gsv/Gata6+ (more )
Structure Level Pattern Image Note
TS6: embryo Absent 5C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory