Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Igs13tm1Dolm
Name:	intergenic site 13; targeted mutation 1, Ricardo Dolmetsch
MGI ID:	MGI:5569502
Gene:	Igs13  Location: unknown  Genetic Position: Chr7, Syntenic
Alliance:	Igs13tm1Dolm page

Germline Transmission:	Earliest citation of germline transmission: J:210018
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting vector is designed to insert a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (from pCAGGS), loxP-frt-neomycin resistance cassette-loxP-frt-loxP sequence and polyA signal at the centromeric end of the coronin actin binding protein 1A locus (Coro1a) gene. The insertion site is 1165 bp centromeric (transcriptionally downstream) of the last exon. (J:210018)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igs13 Mutation:	1 strain or line available

Original:	J:210018 Portmann T, et al., Behavioral abnormalities and circuit defects in the Basal Ganglia of a mouse model of 16p11.2 deletion syndrome. Cell Rep. 2014 May 22;7(4):1077-92
All:	4 reference(s)