Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Cspg4-EGFP*)HDbe
Name:	transgene insertion H, Dwight E Bergles
MGI ID:	MGI:5568765
Synonyms:	NG2-mEGFP, NG2-mEGFP-H
Transgene:	Tg(Cspg4-EGFP*)HDbe  Location: unknown
Alliance:	Tg(Cspg4-EGFP*)HDbe page

Strain of Origin:

B6SJLF1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: Bacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-309G21) containing the entire mouse Cspg4 (chondroitin sulfate proteoglycan 4) gene. The BAC was modified to create a membrane anchored form of EGFP (enhanced green fluorescent protein) under the control of the Cspg4 promoter followed by a polyadenylation sequence. EGFP is targeted to the plasma membrane by fusing the first 26 amino acids (containing two palmitoylation domains and a myristoylation domain) of Lck (lymphocyte-specific protein tyrosine kinase) to the EGFP N terminal. (J:209866)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:209866 Hughes EG, et al., Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain. Nat Neurosci. 2013 Jun;16(6):668-76
All:	4 reference(s)