Tg(Pcp2-COP4*H134R/EYFP)U126Isop
Transgene Detail
|
|
| Symbol: |
Tg(Pcp2-COP4*H134R/EYFP)U126Isop |
| Name: |
transgene insertion U126, Philippe Isope |
| MGI ID: |
MGI:5568417 |
| Synonyms: |
L7-ChR2, L7-ChR2(H134R)-eYFP |
| Transgene: |
Tg(Pcp2-COP4*H134R/EYFP)U126Isop Location: unknown
|
| Alliance: |
Tg(Pcp2-COP4*H134R/EYFP)U126Isop page
|
|
|
|
| Transgene Type: |
|
Transgenic (Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: I.M.A.G.E. clone BAC RP24-186D18 was modified to express a cDNA encoding humanized COP4 (also called channelrhodopsin-2 or ChR2) carrying an H134R (histidine 134 arginine) mutation fused to EYFP (ChR2(H134R)EFYP) under the control of the mouse Pcp2 gene regulatory elements. High expression is found in Purkinje cells of the cerebellum as well as rod bipolar cells of the retina.
(J:201128)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:201128 Chaumont J, et al., Clusters of cerebellar Purkinje cells control their afferent climbing fiber discharge. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16223-16228 |
| All: |
1 reference(s) |
|
Analysis Tools
