Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Fbxw11tm1.1Ybn
Name:	F-box and WD-40 domain protein 11; targeted mutation 1.1, Yinon Ben-Neriah
MGI ID:	MGI:5568205
Synonyms:	beta-TrCP2f
Gene:	Fbxw11  Location: Chr11:32592724-32696816 bp, + strand  Genetic Position: Chr11, 19.02 cM
Alliance:	Fbxw11tm1.1Ybn page

Germline Transmission:	Earliest citation of germline transmission: J:206654
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: The targeting vector was designed to insert a loxP-flanked neomycin cassette and a third loxP site was used to flank exon 4. The neomycin cassette was removed by breeding to recombinase-expressing mice. (J:101977, J:206654)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fbxw11 Mutation:	71 strains or lines available

Original:	J:206654 Kanarek N, et al., Critical role for IL-1beta in DNA damage-induced mucositis. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E702-11
All:	2 reference(s)