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Gene Expression Data
Assay Details
Assay
Reference: J:137184 Fogelgren B, et al., Misexpression of Six2 is associated with heritable frontonasal dysplasia and renal hypoplasia in 3H1 Br mice. Dev Dyn. 2008 Jul;237(7):1767-79
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5565353
Gene symbol: Six2
Gene name: sine oculis-related homeobox 2
Antibody: anti-Six2
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 7A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head mesenchyme derived from neural crest Present 7A
TS19: medial-nasal process mesenchyme Present 7A
TS19: olfactory epithelium Present 7A
TS19: head mesenchyme Present Regionally restricted 7A Expression is in the midline mesenchyme, extending dorsally into the developing chondrocranium.
TS19: latero-nasal process Present Regionally restricted 7A Expression is in a small group of subepithelial cells in the rostral tip.
Specimen 7B: embryonic day 11.5; Br/Br (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Absent 7B
TS19: head mesenchyme derived from neural crest Absent 7B
TS19: latero-nasal process Absent 7B
TS19: medial-nasal process mesenchyme Absent 7B
TS19: olfactory epithelium Absent 7B
Specimen 7C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: medial-nasal process mesenchyme Present 7C
TS19: olfactory epithelium Present 7C
TS19: head mesenchyme Present Regionally restricted 7C Expression is in the midline mesenchyme, extending dorsally into the developing chondrocranium.
TS19: latero-nasal process Present Regionally restricted 7C Expression is in a small group of subepithelial cells in the rostral tip.
Specimen 7D: embryonic day 11.5; Br/Br (more )
Structure Level Pattern Image Note
TS19: head mesenchyme Absent 7D
TS19: latero-nasal process Absent 7D
TS19: medial-nasal process mesenchyme Absent 7D
TS19: olfactory epithelium Absent 7D
Specimen 7E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 7E Expression is surrounding the ureteric bud tubule.
Specimen 7F: embryonic day 11.5; Br/Br (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Absent 7F
Specimen 7G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 7G Expression is around the periphery of the developing kidney in the undifferentiated metanephric mesenchyme cells.
Specimen 7H: embryonic day 14.5; Br/Br (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Absent 7H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory