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Gene Expression Data
Assay Details
Assay
Reference: J:142644 Mahtab EA, et al., Podoplanin deficient mice show a rhoa-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Dev Dyn. 2008 Dec 18;238(1):183-193
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5563348
Gene symbol: Hcn4
Gene name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Antibody: anti-HCN4 (APC-052)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2i: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinus venosus Present 2i
TS20: heart Present Regionally restricted 2i Expression is in the sinoatrial node.

Specimen 2k: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: heart Present 2k Expression in this mutant is the same as in wild-type embryos.
TS20: sinus venosus Present 2k Expression in this mutant is the same as in wild-type embryos.

Specimen 3d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinus venosus Present 3d
TS20: cardinal vein Present Regionally restricted 3d Expression is in the wall.
TS20: venous system Present Regionally restricted 3d Expression is in the wall of the pulmonary vein.

Specimen 3f: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: sinus venosus Present 3f
TS20: venous system Trace Regionally restricted 3f Nearly absent in expression due to lack of myocardium of the pulmonary vein.

Specimen 3m: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinus venosus Present 3m
TS20: cardinal vein Present Regionally restricted 3m Expression is in the wall.
TS20: venous system Present Regionally restricted 3m Expression is in the wall of the pulmonary vein.

Specimen 3o: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: sinus venosus Present 3o


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory