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Gene Expression Data
Assay Details
Assay
Reference: J:142644 Mahtab EA, et al., Podoplanin deficient mice show a rhoa-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Dev Dyn. 2008 Dec 18;238(1):183-193
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5563347
Gene symbol: Nkx2-5
Gene name: NK2 homeobox 5
Antibody: anti-Nkx-2.5 (N-19): sc-8697
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2g: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: sinus venosus Absent 2g
Specimen 2j: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: sinus venosus Absent 2j
Specimen 3h,i: embryonic day 12.5 (more )
Note: i is a higher magnification of the boxed area in h.
Structure Level Pattern Image Note
TS20: venous system Present Regionally restricted 3h , 3i Mosaic expression in the myocardium lining the pulmonary vein.
TS20: cardinal vein Absent 3h , 3i
TS20: sinus venosus Absent 3h , 3i
Specimen 3j,k: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Note: j is a higher magnification of the boxed area in k.
Structure Level Pattern Image Note
TS20: venous system Trace Regionally restricted 3j , 3k Nearly absent in this hypoplastic area of the myocardium lining the pulmonary vein.
TS20: sinus venosus Absent 3k , 3j
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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