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Gene Expression Data
Assay Details
Assay
Reference: J:142644 Mahtab EA, et al., Podoplanin deficient mice show a rhoa-related hypoplasia of the sinus venosus myocardium including the sinoatrial node. Dev Dyn. 2008 Dec 18;238(1):183-193
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5563346
Gene symbol: Myl7
Gene name: myosin, light polypeptide 7, regulatory
Antibody: MLC-2a antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2c,d: embryonic day 12.5 (more )
Note: d is a higher magnification of the boxed area in c.
Structure Level Pattern Image Note
TS20: sinus venosus Present 2d , 2c
TS20: heart Present 2c , 2d Expression is in the sinoatrial node.
TS20: atrium cardiac muscle Present 2c , 2d
TS20: ventricle cardiac muscle Present 2c , 2d
Specimen 2e,f: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Note: f is a higher magnification of the boxed area in e.
Structure Level Pattern Image Note
TS20: sinus venosus Present 2e , 2f Expression in this mutant is the same as in wild-type embryos.
TS20: heart Present Regionally restricted 2f , 2e Expression is in the sinoatrial node. Expression in this mutant is the same as in wild-type embryos.
TS20: atrium cardiac muscle Present 2e , 2f Expression in this mutant is the same as in wild-type embryos.
TS20: ventricle cardiac muscle Present 2e , 2f Expression in this mutant is the same as in wild-type embryos.
Specimen 3c: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrium cardiac muscle Present 3c
TS20: sinus venosus Present 3c
TS20: ventricle cardiac muscle Present 3c
TS20: cardinal vein Present Regionally restricted 3c Expression is in the wall.
TS20: venous system Present Regionally restricted 3c Expression is in the wall of the pulmonary vein.
Specimen 3e: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: atrium cardiac muscle Present 3e Expression in this mutant is the same as in wild-type embryos.
TS20: sinus venosus Present 3e Expression in this mutant is the same as in wild-type embryos.
TS20: ventricle cardiac muscle Present 3e Expression in this mutant is the same as in wild-type embryos.
Specimen 3l: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: atrium cardiac muscle Present 3l
TS20: sinus venosus Present 3l
TS20: ventricle cardiac muscle Present 3l
TS20: cardinal vein Present Regionally restricted 3l Expression is in the wall.
TS20: venous system Present Regionally restricted 3l Expression is in the wall of the pulmonary vein.
Specimen 3n: embryonic day 12.5; Pdpntm1Acgg/Pdpntm1Acgg (more )
Structure Level Pattern Image Note
TS20: atrium cardiac muscle Present 3n Expression in this mutant is the same as in wild-type embryos.
TS20: sinus venosus Present 3n Expression in this mutant is the same as in wild-type embryos.
TS20: ventricle cardiac muscle Present 3n Expression in this mutant is the same as in wild-type embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory