Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Hcn4-cre/ERT2)1Yzhao
Name:	transgene insertion 1, Yong Zhao
MGI ID:	MGI:5562295
Synonyms:	Hcn4-CreERT2
Transgene:	Tg(Hcn4-cre/ERT2)1Yzhao  Location: unknown
Alliance:	Tg(Hcn4-cre/ERT2)1Yzhao page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Hcn4-cre/ERT2)1Yzhao expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Hcn4   Mutation details: Recombineering methods were used to insert a cre/ERT2 cassette immediately after the ATG start codon of the Hcn4 locus in a bacterial artificial chromosome (this BAC does not encode other proteins or micro RNAs). The BAC construct was purified and used for pronuclear injection of fertilized oocytes. Two founders were generated, with essentially identical cre activity patterns following tamoxifen treatment being observed. One line was chosen for detailed analyses. (J:207828)

Generation of Tg(Hcn4-cre/ERT2)1Yzhao.

Activity:	Tissue activity of this recombinase allele
Driver:	Hcn4 (species not specified) Summary of all recombinase alleles driven by Hcn4. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:207828 Wu M, et al., Inducible gene deletion in the entire cardiac conduction system using Hcn4-CreERT2 BAC transgenic mice. Genesis. 2014 Feb;52(2):134-40
All:	3 reference(s)