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Gene Expression Data
Assay Details
Assay
Reference: J:138800 De Gasperi R, et al., Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling. Dev Dyn. 2008 Sep;237(9):2405-14
Assay type: Western blot
MGI Accession ID: MGI:5561060
Gene symbol: Dab1
Gene name: disabled 1
Antibody: Dab1 Antibody
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The protein was immunoprecipitated prior to Western blotting. An antibody recognizing phosphotyrosine was used to test the phsphorylated form (summarized in Fig. 1C).
Results
Image: 1A Dab1 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
E18.5 +/- E18.5 TS26: brain Present involves: 129S7/SvEvBrd Psen1tm1Shn/Psen1+Not Specified
E18.5 +/+ E18.5 TS26: brain Present Not Specified Not Specified
E18.5 -/- E18.5 TS26: brain Present (a) involves: 129S7/SvEvBrd Psen1tm1Shn/Psen1tm1ShnNot Specified
E18.5 -/- E18.5 TS26: brain Present (a) involves: 129S7/SvEvBrd Psen1tm1Shn/Psen1tm1ShnNot Specified
E18.5 +/- E18.5 TS26: brain Present involves: 129S7/SvEvBrd Psen1tm1Shn/Psen1+Not Specified
E18.5 +/- E18.5 TS26: brain Present involves: 129S7/SvEvBrd Psen1tm1Shn/Psen1+Not Specified
Notes:
(a) Total protein levels were unaltered, but phosphorylated levels were significantly decreased.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory