Tg(Tmc2/AcGFP)3Ajg
Transgene Detail
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| Symbol: |
Tg(Tmc2/AcGFP)3Ajg |
| Name: |
transgene insertion 3, Andrew Griffith |
| MGI ID: |
MGI:5560295 |
| Synonyms: |
Tg(RP24-293G8/Tmc2/AcGFP)3Ajg, Tmc2-AcGFP |
| Transgene: |
Tg(Tmc2/AcGFP)3Ajg Location: unknown
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| Alliance: |
Tg(Tmc2/AcGFP)3Ajg page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Tg(Tmc2/AcGFP)3Ajg expresses
1 gene
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Mutation details: The transgene was created by targeted insertion of Aequorea coerulescens green fluorescent protein (AcGFP) coding sequence into the bacterial artificial chromosome (BAC) RP24-293G8. The AcGFP sequence integrated at the stop codon of Tmc2. The integration site was not investigated. The C-terminal fusion is expressed in the sensory hair cells of the inner ear.
The modified BAC also carries the Snrpb, Nop56, and Idh3b genes. Line 3 carries 3 copies of the transgene.
(J:226895)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:226895 Kurima K, et al., TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia. Cell Rep. 2015 Sep 8;12(10):1606-17 |
| All: |
3 reference(s) |
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Analysis Tools
