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Gene Expression Data
Assay Details
Assay
Reference: J:138805 Ikegawa M, et al., Syndactyly and preaxial synpolydactyly in the single Sfrp2 deleted mutant mice. Dev Dyn. 2008 Sep;237(9):2506-17
Assay type: RNA in situ
MGI Accession ID: MGI:5560282
Gene symbol: Sfrp1
Gene name: secreted frizzled-related protein 1
Probe: Sfrp1 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 6f WT FL: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 6f WT FL Expression was detected in the mesenchyme surrounding newly formed cartilage in the distal limb.

Specimen 6f Mutant FL: embryonic day 13.5; Sfrp2tm1Ktas/Sfrp2tm1Ktas (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 6f Mutant FL Expression was slightly upregulated or almost the same as in wild type.

Specimen 6f WT HL: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted 6f WT HL Expression was detected in the mesenchyme surrounding newly formed cartilage in the distal limb.

Specimen 6f Mutant HL: embryonic day 13.5; Sfrp2tm1Ktas/Sfrp2tm1Ktas (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted 6f Mutant HL Expression was slightly upregulated or almost the same as in wild type.

Specimen S3a FL: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: hand joint Present Regionally restricted S3a FL Expression was detected in the presumptive joint area, with a mildly predominant expression in the distal margins.

Specimen S3a HL: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: foot joint Present Regionally restricted S3a HL Expression was detected in the presumptive joint area, with a mildly predominant expression in the distal margins.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory