Gene Expression Data
Assay Details
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Assay
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Reference:
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J:203658
Yariz KO, et al., Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss. Am J Hum Genet. 2012 Nov 2;91(5):872-82
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5556390
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Gene symbol:
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Otogl
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Gene name:
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otogelin-like
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Results
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Specimen
3A:
embryonic day 17.5
(more  )
Note: Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
Specimen
3A:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 17.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: cochlea |
Present |
Regionally restricted |
3A
,
3A'
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Expression is present on the lumen surface of interdental cells close to the Reissner's membrane and the base of tectorial membrane.
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| TS25: cochlear duct |
Present |
Regionally restricted |
3A'
,
3A
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Expression is present in the spiral prominence.
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| TS25: organ of Corti |
Present |
Non-Uniform |
3A
,
3A'
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Expression is present in the Claudius cells and weakly in hair cells.
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Specimen
3C:
postnatal day 0
(more )
Note: Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
Specimen
3C:
(close )
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Genetic Background:
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CD-1
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: cochlea |
Present |
Non-Uniform |
3C
,
3C''
,
3C'
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There is clear staining in the Deiters cells. Expression is also present on the lumen surface of interdental cells close to the Reissner's membrane.
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| TS27: spiral prominence |
Present |
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3C
,
3C''
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3C'
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| TS27: organ of Corti |
Present |
Non-Uniform |
3C
,
3C''
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3C'
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Expression is present in the Claudius cells and in hair cells.
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| TS27: tectorial membrane |
Present |
Non-Uniform |
3C''
,
3C'
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3C
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Expression is present at the base.
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Specimen
3D:
postnatal day 0
(more )
Note: Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
Specimen
3D:
(close )
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Genetic Background:
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CD-1
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: saccule |
Present |
Non-Uniform |
3D'
,
3D
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There is prominent expression in the saccular roof, likely in the otolithic membrane. There is weak expression in the hair cells.
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Specimen
3F:
postnatal day 6
(more )
Note: Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
Specimen
3F:
(close )
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Genetic Background:
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CD-1
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cochlear duct |
Present |
Regionally restricted |
3F'
,
3F''
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3F
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Expression is present in the Deiters cells.
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| TS28: organ of Corti |
Present |
Regionally restricted |
3F''
,
3F'
,
3F
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Expression is restricted to outer hair cells, Pillar cells and Claudius cells.
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| TS28: tectorial membrane |
Present |
Regionally restricted |
3F''
,
3F'
,
3F
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Expression is restricted to the base.
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Specimen
3H:
postnatal day 6
(more )
Note: Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
Specimen
3H:
(close )
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Genetic Background:
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CD-1
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Age:
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postnatal day 6
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Triple labeled: red - Otogl; green - Myo7a (assay MGI:5559193); white - Sox2 (assay MGI:5559197).
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: saccule |
Present |
Regionally restricted |
3H'
,
3H
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There is strong staining in the roof. Expression in the hair cells is still weak.
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Analysis Tools