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Tg(hs1163-Ccre,-lacZ)1Fawa
Transgene Detail
Summary
Symbol: Tg(hs1163-Ccre,-lacZ)1Fawa
Name: transgene insertion 1, Fan Wang
MGI ID: MGI:5556214
Synonyms: CreC1163
Transgene: Tg(hs1163-Ccre,-lacZ)1Fawa  Location: unknown  
Alliance: Tg(hs1163-Ccre,-lacZ)1Fawa page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(hs1163-Ccre,-lacZ)1Fawa expression driven by 1 gene
 
Mutation detailsThe C-terminal fragment of cre recombinase (aa 60-343) fused to the intein-C peptide fragment (36 C terminal amino acids) of the DnaE split intein sequence was cloned into a vector containing the human enhancer 1163 sequence (hs1163) and an Hsp68 minimal promoter and lacZ reporter. The final construct included an IRES sequence separating the lacZ gene and Ccre-intein-C. Injection of the linearized construct into pronuclei was performed to generated transgenic founders. Line numbers were not identified in the publication. (J:207270)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: hs1163 (human)
Summary of all recombinase alleles driven by hs1163.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Examples of reporter expression driven by this and other human enhancers in mouse embryos produced by transient transgenesis can be viewed at http://enhancer.lbl.gov.
References
Original:  J:207270 Wang P, et al., Intersectional Cre driver lines generated using split-intein mediated split-Cre reconstitution. Sci Rep. 2012;2:497
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory