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Gene Expression Data
Assay Details
Assay
Reference: J:163739 Leung AW, et al., Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain. Dev Dyn. 2010 Sep;239(9):2319-29
Assay type: RNA in situ
MGI Accession ID: MGI:5554401
Gene symbol: Col2a1
Gene name: collagen, type II, alpha 1
Probe: pSOK10
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 7.75 (more )
Note: Neural plate stage.
Structure Level Pattern Image Note
TS11: mesendoderm Present Regionally restricted 1A Expression was detected in anterior mesendoderm.
Specimen 1B: embryonic day 8.0 (more )
Note: Early headfold stage.
Structure Level Pattern Image Note
TS11: notochordal plate Present Regionally restricted 1B Expression was detected in the prechordal plate.
TS11: head Present Regionally restricted 1B Expression was detected in the head process.
TS11: definitive endoderm Present Regionally restricted 1B Expression was detected in the anterior definitive endoderm.
Specimen 1i: embryonic day 7.75 (more )
Note: Neural plate stage.
Structure Level Pattern Image Note
TS11: mesendoderm Present Regionally restricted 1i Expression was detected in anterior mesendoderm.
Specimen 1ii: embryonic day 8.0 (more )
Note: Early headfold stage.
Structure Level Pattern Image Note
TS11: notochordal plate Present Regionally restricted 1ii Expression was detected in the prechordal plate.
Specimen 1iii: embryonic day 8.0 (more )
Note: Early headfold stage.
Structure Level Pattern Image Note
TS11: definitive endoderm Present Regionally restricted 1iii Expression was detected in the anterior definitive endoderm. There was overlap with Dkk1 expression.
Specimen 6 IIA: embryonic day 8.0 (more )
Note: 2-4 somites.
Structure Level Pattern Image Note
TS12: head Strong Regionally restricted 6_IIA Expression was detected in the anterior segment of the head process. Expression overlapped with Chrd and Nog.
TS12: heart Strong Regionally restricted 6_IIA Expression was detected in the heart mesoderm.
TS12: notochordal plate Strong 6_IIA Expression was strong in the prechordal plate.
Specimen S1A MS left: embryonic day 7.0 (more )
Note: Mid-streak stage.
Structure Level Pattern Image Note
TS10: embryo Absent S1A MS left
Specimen S1A MS right: embryonic day 7.0 (more )
Note: Mid-streak stage.
Structure Level Pattern Image Note
TS10: embryo Absent S1A MS right
Specimen S1A LS left: embryonic day 7.0 (more )
Note: Late-streak stage.
Structure Level Pattern Image Note
TS10: embryo Absent S1A LS left
Specimen S1A LS right: embryonic day 7.0 (more )
Note: Late-streak stage.
Structure Level Pattern Image Note
TS10: embryo Absent S1A LS right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory