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Gene Expression Data
Assay Details
Assay
Reference: J:100707 Kurita T, et al., Differential expression of p63 isoforms in female reproductive organs. Mech Dev. 2005 Sep;122(9):1043-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5553292
Gene symbol: Trp63
Gene name: transformation related protein 63
Antibody: 4A4
Assay notes: This antibody or a different monoclonal antibody was used for detection MGI:5553154. Both antibodies recognize all six splice isoforms of p63.
Results
Specimen 2B ovary: postnatal adult (more )
Structure Level Pattern Image Note
TS28: oocyte Present 2B p63 ovary
Specimen 2B oviduct: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelial layer of oviduct Present Regionally restricted 2B p63 oviduct Expression is in a subset of epithelial cells in the ampulla of the oviduct.
Specimen 2B uterus: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelial layer of cervix uteri Present 2B p63 uterus Absent in the uterus.
Specimen 2B vagina: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelium of vagina Present 2B p63 vagina
Specimen 2C testis: postnatal adult (more )
Structure Level Pattern Image Note
TS28: germ cell of testis Present 2C p63 testis
TS28: spermatid Strong 2C p63 testis Expression is in the nuclei.
TS28: spermatocyte Strong 2C p63 testis Expression is in the nuclei.
TS28: spermatogonium Trace 2C p63 testis Undetectable to very low expression.
TS28: spermatozoon Absent 2C p63 testis
Specimen 2C seminal vesicle: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epithelium of seminal vesicle Present Regionally restricted 2C p63 seminal vesicle Expression is in basal cells.
Specimen 2C prostate: postnatal adult (more )
Structure Level Pattern Image Note
TS28: prostate epithelium Present Regionally restricted 2C p63 prostate Expression is in basal cells.
Specimen 2C mammary gland: postnatal adult (more )
Structure Level Pattern Image Note
TS28: mammary gland epithelium Present Regionally restricted 2C p63 mammary gland Expression is in myoepithelial cells.
Specimen 2C skin: postnatal adult (more )
Structure Level Pattern Image Note
TS28: epidermis basal layer Present 2C p63 skin
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cloacal epithelium Present 3A p63
Specimen 3C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: urogenital sinus Present 3C
TS24: vagina Present 3C
TS24: paramesonephric duct Absent 3C
Specimen 3D: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: paramesonephric duct Present Graded 3D Expression increased from caudal to cranial in the columnar epithelium.
Specimen 3E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epithelium of vagina Present Regionally restricted 3E p63 inset , 3E p63 Expression is in small numbers of columnar epithelial cells lining the Mullerian vagina.
Specimen 5A: embryonic day 10.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS17: primordial germ cell of hindgut Present 5A insert , 5A Expression in primordial germ cells in hindgut.
TS17: primordial germ cell of gonad Present 5A , 5A insert Expression in primordial germ cells in rudimentary genital ridge.
Specimen 5B: embryonic day 10.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS17: primordial germ cell of hindgut Present 5B Expression in primordial germ cells in hindgut epithelium.
Specimen 5C: embryonic day 10.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS17: primordial germ cell of gonad Present 5C Expression in primordial germ cells in rudimental genital ridge.
Specimen 5D: embryonic day 11.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS19: primordial germ cell of gonad Present 5D Expression in primordial germ cells in urogenital ridge.
Specimen 5E: embryonic day 12.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS20: germ cell of ovary Present 5E
Specimen 5F: embryonic day 14.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS22: germ cell of ovary Strong 5F
Specimen not shown: embryonic day 16.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS24: germ cell of ovary Weak
Specimen 5G: embryonic day 17.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS25: germ cell of ovary Trace 5G
Specimen 5H: embryonic day 18.5 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS26: germ cell of ovary Strong Single cells 5H Some cells were negative for detection.
Specimen 5J: postnatal day 3 (more )
Note: Double labeled with alkaline phosphatase (blue) for primordial germ cells.
Structure Level Pattern Image Note
TS27: oocyte Present 5J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory