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Gene Expression Data
Assay Details
Assay
Reference: J:199077 Nagarajan P, et al., Histone acetyl transferase 1 is essential for mammalian development, genome stability, and the processing of newly synthesized histones H3 and H4. PLoS Genet. 2013 Jun;9(6):e1003518
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5552803
Gene symbol: Hat1
Gene name: histone aminotransferase 1
Antibody: anti-Hat1
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2 WT: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: lung Present 2B WT

Specimen 2 -/-: postnatal newborn; Hat1tm1.1Mrpa/Hat1tm1.1Mrpa (more )
Structure Level Pattern Image Note
TS27: lung Absent 2B HAT1-/-

Specimen 3D +/+: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: head Strong Widespread 3D left
TS20: trunk Strong Widespread 3D left Expression is present in the abdominal region.

Specimen 3D -/-: embryonic day 12.5; Hat1tm1.1Mrpa/Hat1tm1.1Mrpa (more )
Structure Level Pattern Image Note
TS20: embryo Absent 3D right

Specimen 3E +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head Present Widespread 3E left Expression is present in most tissues.

Specimen 3E -/-: embryonic day 11.5; Hat1tm1.1Mrpa/Hat1tm1.1Mrpa (more )
Structure Level Pattern Image Note
TS19: head Absent 3E right

Specimen S1 +/-: embryonic day 11.5; Hat1tm1.1Mrpa/Hat1+ (more )
Structure Level Pattern Image Note
TS19: lung Present S1_Hat1 Hat1+/-

Specimen S1 -/-: embryonic day 11.5; Hat1tm1.1Mrpa/Hat1tm1.1Mrpa (more )
Structure Level Pattern Image Note
TS19: lung Absent S1_Hat1 Hat1-/- Proliferation rates are increased in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory