Tg(Ly6a-cre/ERT2)1Isg
Transgene Detail
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| Symbol: |
Tg(Ly6a-cre/ERT2)1Isg |
| Name: |
transgene insertion 1, Isidro Sanchez-Garcia |
| MGI ID: |
MGI:5551781 |
| Synonyms: |
Sca1-CreERT2 |
| Transgene: |
Tg(Ly6a-cre/ERT2)1Isg Location: unknown
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| Alliance: |
Tg(Ly6a-cre/ERT2)1Isg page
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| Strain of Origin: |
CBA x C57BL/6J
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Ly6a-cre/ERT2)1Isg expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Ly6a |
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Mutation details: cDNA encoding a cre-ERT2 fusion was cloned into a vector containing Ly6a (specifically, a 14 kb Ly6E.1 genomic fragment). A 16 kb fragment was isolated, purified and used for microinjection. Founder/line information is not available.
(J:206384)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ly6a
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:206384 Mainardi S, et al., Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):255-60 |
| All: |
1 reference(s) |
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