Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Ly6a-cre/ERT2)1Isg
Name:	transgene insertion 1, Isidro Sanchez-Garcia
MGI ID:	MGI:5551781
Synonyms:	Sca1-CreERT2
Transgene:	Tg(Ly6a-cre/ERT2)1Isg  Location: unknown
Alliance:	Tg(Ly6a-cre/ERT2)1Isg page

Strain of Origin:

CBA x C57BL/6J

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Ly6a-cre/ERT2)1Isg expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Ly6a   Mutation details: cDNA encoding a cre-ERT2 fusion was cloned into a vector containing Ly6a (specifically, a 14 kb Ly6E.1 genomic fragment). A 16 kb fragment was isolated, purified and used for microinjection. Founder/line information is not available. (J:206384)

Activity:	Tissue activity of this recombinase allele
Driver:	Ly6a (species not specified) Summary of all recombinase alleles driven by Ly6a.

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:206384 Mainardi S, et al., Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma. Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):255-60
All:	1 reference(s)