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Atat1tm1.1Phep
Targeted Allele Detail
Summary
Symbol: Atat1tm1.1Phep
Name: alpha tubulin acetyltransferase 1; targeted mutation 1.1, Paul A Heppenstall
MGI ID: MGI:5549959
Synonyms: Atat1fl
Gene: Atat1  Location: Chr17:36208487-36220967 bp, - strand  Genetic Position: Chr17, 18.75 cM, cytoband B3
Alliance: Atat1tm1.1Phep page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205737
Parent Cell Line:  A9 (ES Cell)
Strain of Origin:  (C57BL/6 x 129P2/OlaHsd)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 6. Flp-mediated recombination removed the selection cassette and left exons 1 through 6 floxed. (J:205737)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atat1 Mutation:  28 strains or lines available
References
Original:  J:205737 Kalebic N, et al., alphaTAT1 is the major alpha-tubulin acetyltransferase in mice. Nat Commun. 2013;4:1962
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory