About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:111612 Uemura M, et al., alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5548092
Gene symbol: Ppp1r1b
Gene name: protein phosphatase 1, regulatory inhibitor subunit 1B
Antibody: anti-DARPP-32
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 4A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 4A Expression is in anterior commissure fibers that elongate towards the midline region.

Specimen 4B: embryonic day 13.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 4B Expression in this mutant is the same as in wild-type.

Specimen 4C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 4C Expression is in anterior commissure fibers that extend close to the midline.

Specimen 4D: embryonic day 14.0; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 4D Expression is present in the anterior commissure which illustrates that fibers are dispersed and far from the midline in this mutant.

Specimen 4E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 4E Expression is in the anterior commissure in fibers that cross the midline.

Specimen 4F: embryonic day 14.5; Ctnna2tm1Mta/Ctnna2tm1Mta (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 4F Expression is present in the anterior commissure which illustrates that fibers are fasciculated and do not cross the midline in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory