Gene Expression Data
Assay Details
Assay
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Reference:
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J:111612
Uemura M, et al., alphaN-catenin deficiency causes defects in axon migration and nuclear organization in restricted regions of the mouse brain. Dev Dyn. 2006 May 11;235(9):2559-2566
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5548092
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Gene symbol:
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Ppp1r1b
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Gene name:
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protein phosphatase 1, regulatory inhibitor subunit 1B
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Antibody:
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anti-DARPP-32
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Results
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Specimen
4A:
embryonic day 13.5
(more )
Specimen
4A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS21: diencephalon |
Present |
Regionally restricted |
4A
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Expression is in anterior commissure fibers that elongate towards the midline region.
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Specimen
4B:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: diencephalon |
Present |
Regionally restricted |
4B
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Expression in this mutant is the same as in wild-type.
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Specimen
4C:
embryonic day 14.0
(more )
Specimen
4C:
(close )
Genetic Background:
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Not Specified
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Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: diencephalon |
Present |
Regionally restricted |
4C
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Expression is in anterior commissure fibers that extend close to the midline.
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Specimen
4D:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
|
embryonic day 14.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: diencephalon |
Present |
Regionally restricted |
4D
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Expression is present in the anterior commissure which illustrates that fibers are dispersed and far from the midline in this mutant.
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Specimen
4E:
embryonic day 14.5
(more )
Specimen
4E:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: diencephalon |
Present |
Regionally restricted |
4E
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Expression is in the anterior commissure in fibers that cross the midline.
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Specimen
4F:
(close )
Genetic Background:
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Not Specified
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Mutant Allele(s):
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Ctnna2tm1Mta/Ctnna2tm1Mta
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Age:
|
embryonic day 14.5
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Sex:
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Not Specified
|
Type:
|
whole mount
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: diencephalon |
Present |
Regionally restricted |
4F
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Expression is present in the anterior commissure which illustrates that fibers are fasciculated and do not cross the midline in this mutant.
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