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Gene Expression Data
Assay Details
Assay
Reference: J:84414 Haraguchi S, et al., nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development. Mech Dev. 2003 Jun;120(6):721-31
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:5545811
Gene symbol: Nanos1
Gene name: nanos C2HC-type zinc finger 1
Reporter: lacZ
Direct Detection
Results
Specimen 4A: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Metaphase II stage oocytes.
Structure Level Pattern Image Note
TS28: secondary oocyte Present 4A
Specimen 4B 8-cell: embryonic day 2.5; Nanos1tm1Ysa/Nanos1+ (more )
Note: 4-cell - blastocyst stage embryos.
Structure Level Pattern Image Note
TS3: 8-cell stage embryo Present 4B 8-cell
Specimen 4B blastocyst: embryonic day 3.5; Nanos1tm1Ysa/Nanos1+ (more )
Note: 4-cell - blastocyst stage embryos.
Structure Level Pattern Image Note
TS4: blastocyst Present 4B blastocyst
Specimen not shown E6.5: embryonic day 6.5; Nanos1tm1Ysa/Nanos1+ (more )
Structure Level Pattern Image Note
TS9: embryo Absent
Specimen not shown E11.5: embryonic day 11.5; Nanos1tm1Ysa/Nanos1+ (more )
Structure Level Pattern Image Note
TS19: embryo Absent
Specimen 4C: embryonic day 12.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Structure Level Pattern Image Note
TS20: central nervous system Present 4C
TS20: genital tubercle Present 4C
TS20: pinna Present 4C
Specimen 4D: embryonic day 14.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Structure Level Pattern Image Note
TS22: central nervous system Present 4D
TS22: genital tubercle Present 4D
TS22: pinna Present 4D
Specimen 4G,H: embryonic day 14.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS22: hippocampus Present 4H , 4G
Specimen 4I: embryonic day 14.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS22: hippocampus Present 4I
TS22: pons Present 4I
Specimen 4J: embryonic day 14.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS22: hippocampus Present 4J
TS22: pons Present 4J
TS22: thalamus Present 4J
Specimen 4K: embryonic day 14.5; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS22: medulla oblongata Present 4K
Specimen 5A: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS28: cerebellum Present 5A
TS28: hippocampus Present 5A
TS28: lateral geniculate nucleus Present 5A
TS28: main olfactory bulb Present 5A
TS28: piriform cortex Present 5A
Specimen 5B: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS28: cerebellum Present 5B
TS28: hippocampus Present 5B
TS28: lateral geniculate nucleus Present 5B
TS28: ventral tegmental area Present 5B
Specimen 5C: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-.
Structure Level Pattern Image Note
TS28: hippocampus Present 5C
TS28: superior colliculus Present 5C
TS28: ventral tegmental area Present 5C
Specimen 5D,E: postnatal adult; Nanos1tm1Ysa/Nanos1+ (more )
Structure Level Pattern Image Note
TS28: dentate gyrus granule cell layer Present 5D , 5E
TS28: dentate gyrus molecular layer Present 5E , 5D Staining in the molecular layer may have been due to expression in the dendrites of granule cells.
TS28: hippocampus CA3 Present 5E , 5D Staining in the CA3 region may have been due to expression in the mossy fiber projections from the dentate gyrus.
TS28: hippocampus CA1 Absent 5D
TS28: hippocampus CA2 Absent 5D
Specimen 5F: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-. Electron microscopy.
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5F Expression was detected in both nerve fibers and nerve terminals.
Specimen 5G: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Note: Specimen was either +/- or -/-. Electron microscopy.
Structure Level Pattern Image Note
TS28: dentate gyrus Present 5G Expression was detected in both nerve fibers and nerve terminals.
Specimen 5J: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Structure Level Pattern Image Note
TS28: oocyte Present 5J Expression was detected in oocytes at various stages of maturation.
Specimen 5K: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Structure Level Pattern Image Note
TS28: seminiferous tubule Present 5K Expression was detected in seminiferous tubules at the spermatid stage.
Specimen 6A: postnatal adult; Nanos1tm1Ysa/Nanos1+ (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 6A Beta-gal staining was higher in the -/- compared to +/-, and the staining pattern differed. Authors indicate the difference between +/- and -/- was due solely to the lacZ allele dosage.
Specimen 6B: postnatal adult; Nanos1tm1Ysa/Nanos1tm1Ysa (more )
Structure Level Pattern Image Note
TS28: hippocampus Present 6B Beta-gal staining was higher in the -/- compared to +/-, and the staining pattern differed. Authors indicate the difference between +/- and -/- was due solely to the lacZ allele dosage.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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