Tg(Foxp3-GFP)90Pkraj
Transgene Detail
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| Symbol: |
Tg(Foxp3-GFP)90Pkraj |
| Name: |
transgene insertion 90, Piotr Kraj |
| MGI ID: |
MGI:5545653 |
| Synonyms: |
Foxp3GFP |
| Transgene: |
Tg(Foxp3-GFP)90Pkraj Location: unknown
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| Alliance: |
Tg(Foxp3-GFP)90Pkraj page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The 186.8 kb C57BL/6 mouse bacterial artificial chromosome (BAC) RP23-446O15 containing the entire Foxp3 gene and other genes, was modified by inserting sequence encoding GFP (Green Fluorescent Protein) followed by a stop codon and the SV40 polyA signal, in frame with the start codon in exon 1 of the Foxp3 gene. None of the other loci on the BAC were modified. The construct is designed to prohibit expression of native or truncated Foxp3 protein.
(J:152306)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:152306 Kuczma M, et al., Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset. J Immunol. 2009 Sep 15;183(6):3731-41 |
| All: |
19 reference(s) |
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Analysis Tools
