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Tnfsf11tm1Suna
Targeted Allele Detail
Summary
Symbol: Tnfsf11tm1Suna
Name: tumor necrosis factor (ligand) superfamily, member 11; targeted mutation 1, Sunao Takeshita
MGI ID: MGI:5544614
Synonyms: Ranklfl
Gene: Tnfsf11  Location: Chr14:78514886-78545483 bp, - strand  Genetic Position: Chr14, 41.26 cM
Alliance: Tnfsf11tm1Suna page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:201631
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 4. (J:201631, J:233242)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfsf11 Mutation:  30 strains or lines available
References
Original:  J:201631 Takeshita S, et al., Osteoclast-secreted CTHRC1 in the coupling of bone resorption to formation. J Clin Invest. 2013 Sep 3;123(9):3914-24
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory