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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5542041
Gene symbol: Ano1
Gene name: anoctamin 1, calcium activated chloride channel
Probe: RIKEN clone 4732479D23 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7384: embryonic day 10.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7384
TS17: mesonephros Present GUDMAP:7384 there may be some signal in the mesenchyme surrounding the nephric duct.
TS17: mesonephric tubule Present GUDMAP:7384 signal is present in the mesonephric glomeruli
TS17: nephric duct, mesonephric portion Present GUDMAP:7384
TS17: nephric duct, metanephric portion Present GUDMAP:7384
TS17: gonad primordium Absent GUDMAP:7384
TS17: rest of cranial mesonephric tubule Present GUDMAP:7384
TS17: cranial mesonephric tubule Present GUDMAP:7384
TS17: caudal mesonephric tubule Present GUDMAP:7384
Specimen GUDMAP:7385: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7385
TS20: metanephros Present Regionally restricted GUDMAP:7385
TS20: early nephron Present GUDMAP:7385
TS20: primitive bladder Present Regionally restricted GUDMAP:7385 signal appears to be restricted to the epithelial layer of the primitive bladder and possible detrusor muscle layer
TS20: urogenital mesentery Absent GUDMAP:7385
TS20: ureteric tip Absent GUDMAP:7385
Specimen GUDMAP:7386: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: male reproductive system Present GUDMAP:7386
TS20: mesonephros of male Present GUDMAP:7386
TS20: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7386 graded expression; regionally restricted pattern appears strongest along the lateral half and very strong surrounding the nephric duct with weak signal on the medial half with moderate signal along the junction where the mesonephros meets the testis
TS20: testis Absent GUDMAP:7386
TS20: urogenital mesentery Absent GUDMAP:7386
Specimen GUDMAP:7387: embryonic day 12.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS20: female reproductive system Present GUDMAP:7387
TS20: mesonephros of female Present GUDMAP:7387 it is unclear if there is signal within the ducts of the mesonephros because the signal is very strong therefore
TS20: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7387 graded expression; strongest along the lateral edge with a gradient moving medially and very strong surrounding the nephric and paramesonephric ducts
TS20: ovary Absent GUDMAP:7387
TS20: urogenital mesentery Absent GUDMAP:7387
TS20: paramesonephric duct of female, mesonephric portion Absent GUDMAP:7387
Specimen GUDMAP:7747: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: male reproductive system Present GUDMAP:7747
TS23: mesonephros of male Present GUDMAP:7747
TS23: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7747 specific strong expression in subset of mesenchyme surrounding the paramesonephric duct
TS23: degenerating mesonephric portion of male paramesonephric duct Present GUDMAP:7747 signal restricted to the mesenchyme of the duct; signal absent from the duct epithelium
TS23: cranial mesonephric tubule of male Present GUDMAP:7747
TS23: coelomic epithelium of male mesonephros Present GUDMAP:7747
TS23: testis Present GUDMAP:7747 weak expression
TS23: coelomic epithelium of testis Present GUDMAP:7747
TS23: seminiferous cord Present GUDMAP:7747
Specimen GUDMAP:7748: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: bladder Present GUDMAP:7748
TS23: urothelium of bladder Present GUDMAP:7748
TS23: detrusor muscle of bladder Present GUDMAP:7748 expression in a subset of detrusor muscle adjacent to muscularis mucosa layer
Specimen GUDMAP:7749: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:7749
Specimen GUDMAP:7750: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: epididymis Present GUDMAP:7750
TS28: epithelium of epididymis Present GUDMAP:7750
TS28: muscle layer of epididymis Present GUDMAP:7750
TS28: testis Absent GUDMAP:7750
TS28: adventitia of epididymis Absent GUDMAP:7750
Specimen GUDMAP:7751: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: ovary Absent GUDMAP:7751
TS28: oviduct Absent GUDMAP:7751
Specimen GUDMAP:7817: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: female reproductive system Present GUDMAP:7817
TS23: ovary Present GUDMAP:7817
TS23: surface epithelium of ovary Present GUDMAP:7817
TS23: mesonephros of female Present GUDMAP:7817
TS23: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7817 graded expression; possible gradient of expression strongest surrounding the paramesonephric duct and surrounding the degenerating nephric duct
TS23: coelomic epithelium of female mesonephros Present GUDMAP:7817
TS23: paramesonephric duct of female, mesonephric portion Absent GUDMAP:7817
TS23: degenerating mesonephric portion of nephric duct of female Absent GUDMAP:7817
Specimen GUDMAP:7867: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: metanephros Present GUDMAP:7867
TS23: nephrogenic zone Present GUDMAP:7867
TS23: ureteric tip Present GUDMAP:7867
TS23: ureteric tree terminal branch excluding tip itself Present GUDMAP:7867
TS23: cap mesenchyme Present GUDMAP:7867
TS23: nephrogenic interstitium Present GUDMAP:7867
TS23: pretubular aggregate Present GUDMAP:7867
TS23: renal cortex Present GUDMAP:7867
TS23: renal vesicle Present GUDMAP:7867
TS23: comma-shaped body Present Regionally restricted GUDMAP:7867
TS23: s-shaped body Present Regionally restricted GUDMAP:7867
TS23: capillary loop renal corpuscle Present GUDMAP:7867
TS23: presumptive mesangium of capillary loop renal corpuscle Present GUDMAP:7867 strong signal
TS23: maturing renal corpuscle Present GUDMAP:7867
TS23: glomerular capillary system of maturing glomerular tuft Present GUDMAP:7867
TS23: glomerular mesangium of maturing glomerular tuft Present GUDMAP:7867 strong signal
TS23: cortical renal tubule Present GUDMAP:7867 subset of tubules show no expression
TS23: renal cortical interstitium Present GUDMAP:7867
TS23: renal cortical vasculature Present GUDMAP:7867
TS23: renal medulla Present GUDMAP:7867
TS23: renal medullary interstitium Present GUDMAP:7867 stronger signal than cortical interstitium; strong signal
TS23: immature loop of Henle Present GUDMAP:7867
TS23: renal pelvis Present GUDMAP:7867 strong signal
TS23: pelvic urothelial lining Present GUDMAP:7867
TS23: pelvic smooth muscle Present GUDMAP:7867
TS23: ureter Present GUDMAP:7867 strong signal
TS23: urothelium of ureter Present GUDMAP:7867
TS23: ureteral mesenchyme Present GUDMAP:7867
TS23: ureteral smooth muscle layer Present GUDMAP:7867
TS23: ureteral mesenchyme outer layer Absent GUDMAP:7867
TS23: visceral epithelium of capillary loop renal corpuscle Ambiguous GUDMAP:7867
TS23: parietal epithelium of capillary loop renal corpuscle Ambiguous GUDMAP:7867
TS23: visceral epithelium of maturing renal corpuscle Ambiguous GUDMAP:7867
TS23: cortical early proximal tubule Ambiguous GUDMAP:7867
TS23: anlage of loop of Henle of cortical renal tubule Ambiguous GUDMAP:7867
TS23: cortical early distal tubule Ambiguous GUDMAP:7867
Specimen GUDMAP:7868: postnatal adult (more )
Note: Labeling was visualized using BM purple.
Structure Cell Type Level Pattern Image Note
TS28: male reproductive system Present GUDMAP:7868
TS28: testis Present GUDMAP:7868
TS28: seminiferous tubule Present GUDMAP:7868 signal is restricted to a subset of seminiferous tubules
TS28: Sertoli cell Sertoli cell Present GUDMAP:7868
TS28: epididymis Present GUDMAP:7868
TS28: epithelium of epididymis Present GUDMAP:7868
Specimen GUDMAP:8894: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: metanephros Present Regionally restricted GUDMAP:8894
TS23: nephrogenic zone Present GUDMAP:8894
TS23: ureteric tip Present Regionally restricted GUDMAP:8894 expression restricted to a subset of ureteric tips especially seen in the perihilar region of the metanephros
TS23: renal cortex Present GUDMAP:8894
TS23: renal vesicle Present GUDMAP:8894 expression observed in both ends of renal vesicle
TS23: comma-shaped body Present GUDMAP:8894
TS23: s-shaped body Present GUDMAP:8894
TS23: distal segment of s-shaped body Present GUDMAP:8894
TS23: medial segment of s-shaped body Present GUDMAP:8894
TS23: proximal segment of s-shaped body Present GUDMAP:8894
TS23: capillary loop renal corpuscle Present GUDMAP:8894
TS23: presumptive mesangium of capillary loop renal corpuscle Present GUDMAP:8894
TS23: maturing renal corpuscle Present GUDMAP:8894
TS23: maturing glomerular tuft Present GUDMAP:8894
TS23: glomerular mesangium of maturing glomerular tuft Present GUDMAP:8894
TS23: juxtaglomerular arteriole Present GUDMAP:8894
TS23: renal cortical interstitium Present Regionally restricted GUDMAP:8894 spotted expression
TS23: renal cortical vasculature Present GUDMAP:8894
TS23: renal cortical arterial system Present GUDMAP:8894
TS23: renal medulla Present GUDMAP:8894
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:8894 spotted expression; expression restricted to region surrounding medullary collecting ducts and immature loop of Henle
TS23: renal pelvis Present GUDMAP:8894
TS23: ureter Present GUDMAP:8894
TS23: urothelium of ureter Present GUDMAP:8894
TS23: ureteral mesenchyme Present GUDMAP:8894
TS23: ureteral smooth muscle layer Present GUDMAP:8894
TS23: renal interstitium Present GUDMAP:8894
TS23: renal vasculature Present GUDMAP:8894
TS23: developing capillary loop stage nephron group Present GUDMAP:8894
TS23: maturing nephron Present GUDMAP:8894
TS23: cortical renal tubule Present Regionally restricted GUDMAP:8894 expression only detected in tubules of capillary loop nephrons
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:8894 expression only detected in tubules of capillary loop nephrons
TS23: anlage of loop of Henle of cortical renal tubule Present Regionally restricted GUDMAP:8894 expression detected in tubules of capillary loop nephrons
TS23: renal capsule Absent GUDMAP:8894
TS23: cap mesenchyme Absent GUDMAP:8894
TS23: nephrogenic interstitium Absent GUDMAP:8894
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8894
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8894
TS23: cortical collecting duct Absent GUDMAP:8894
TS23: collecting duct Absent GUDMAP:8894
TS23: medullary collecting duct Absent GUDMAP:8894
TS23: perihilar interstitium Absent GUDMAP:8894
TS23: ureteral mesenchyme outer layer Absent GUDMAP:8894
TS23: immature loop of Henle Ambiguous GUDMAP:8894 uncertain weak signal in a subset of loop of Henle
TS23: pelvic urothelial lining Ambiguous GUDMAP:8894
TS23: pretubular aggregate Ambiguous GUDMAP:8894 possible expression in a subset of later stage aggregates
TS23: cortical renal tubule of capillary loop nephron group Present GUDMAP:8894
TS23: early proximal tubule of capillary loop nephron Present GUDMAP:8894
TS23: cortical renal tubule of maturing nephron group Absent GUDMAP:8894
Specimen GUDMAP:8895: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Present Regionally restricted GUDMAP:8895
TS23: urothelium of ureter Present GUDMAP:8895
TS23: ureteral mesenchyme Present GUDMAP:8895
TS23: ureteral smooth muscle layer Present GUDMAP:8895
TS23: ureteral mesenchyme outer layer Absent GUDMAP:8895
TS23: urogenital mesentery Absent GUDMAP:8895
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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