Fmo2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type:	RNA in situ
MGI Accession ID:	MGI:5541990
Gene symbol:	Fmo2
Gene name:	flavin containing monooxygenase 2

Probe:	RIKEN clone 2310042I22 subclone
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

GUDMAP:9128 ©

Specimen GUDMAP:9128: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS23: urinary system	Present	Regionally restricted	GUDMAP:9128
TS23: metanephros	Present	Regionally restricted	GUDMAP:9128
TS23: renal cortex	Present	Regionally restricted	GUDMAP:9128
TS23: cortical renal tubule	Present	Regionally restricted	GUDMAP:9128	strong expression in subset of tubules of maturing nephrons only including early proximal
TS23: cortical early proximal tubule	Present	Regionally restricted	GUDMAP:9128	distal expression; expression restricted to a subset of the early proximal. Expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
TS23: maturing nephron	Present	Regionally restricted	GUDMAP:9128
TS23: late tubule	Present	Regionally restricted	GUDMAP:9128
TS23: renal capsule	Absent		GUDMAP:9128
TS23: nephrogenic zone	Absent		GUDMAP:9128
TS23: nephrogenic interstitium	Absent		GUDMAP:9128
TS23: cap mesenchyme	Absent		GUDMAP:9128
TS23: pretubular aggregate	Absent		GUDMAP:9128
TS23: ureteric tip	Absent		GUDMAP:9128
TS23: ureteric tree terminal branch excluding tip itself	Absent		GUDMAP:9128
TS23: renal vesicle	Absent		GUDMAP:9128
TS23: comma-shaped body	Absent		GUDMAP:9128
TS23: upper limb of comma-shaped body	Absent		GUDMAP:9128
TS23: lower limb of comma-shaped body	Absent		GUDMAP:9128
TS23: s-shaped body	Absent		GUDMAP:9128
TS23: renal connecting tubule of s-shaped body	Absent		GUDMAP:9128
TS23: distal segment of s-shaped body	Absent		GUDMAP:9128
TS23: medial segment of s-shaped body	Absent		GUDMAP:9128
TS23: proximal segment of s-shaped body	Absent		GUDMAP:9128
TS23: visceral epithelium of s-shaped body	Absent		GUDMAP:9128
TS23: parietal epithelium of s-shaped body	Absent		GUDMAP:9128
TS23: capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: visceral epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: parietal epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: presumptive mesangium of capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: presumptive endothelium of capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: associated interstitium of capillary loop renal corpuscle	Absent		GUDMAP:9128
TS23: maturing renal corpuscle	Absent		GUDMAP:9128
TS23: maturing glomerular tuft	Absent		GUDMAP:9128
TS23: glomerular capillary system of maturing glomerular tuft	Absent		GUDMAP:9128
TS23: glomerular basement membrane of maturing renal corpuscle	Absent		GUDMAP:9128
TS23: glomerular mesangium of maturing glomerular tuft	Absent		GUDMAP:9128
TS23: visceral epithelium of maturing renal corpuscle	Absent		GUDMAP:9128
TS23: Bowman's capsule of maturing renal corpuscle	Absent		GUDMAP:9128
TS23: parietal epithelium of maturing renal corpuscle	Absent		GUDMAP:9128
TS23: glomerular mesangium of maturing renal corpuscle	Absent		GUDMAP:9128
TS23: juxtaglomerular arteriole	Absent		GUDMAP:9128
TS23: anlage of loop of Henle of cortical renal tubule	Absent		GUDMAP:9128
TS23: cortical collecting duct	Absent		GUDMAP:9128
TS23: renal cortical interstitium	Absent		GUDMAP:9128
TS23: renal cortical vasculature	Absent		GUDMAP:9128
TS23: renal cortical arterial system	Absent		GUDMAP:9128
TS23: renal cortical venous system	Absent		GUDMAP:9128
TS23: renal cortical capillary	Absent		GUDMAP:9128
TS23: renal connecting tubule	Absent		GUDMAP:9128
TS23: renal medulla	Absent		GUDMAP:9128
TS23: immature loop of Henle	Absent		GUDMAP:9128
TS23: straight limb of immature loop of Henle	Absent		GUDMAP:9128
TS23: bend of immature loop of Henle	Absent		GUDMAP:9128
TS23: renal medullary interstitium	Absent		GUDMAP:9128
TS23: renal medullary vasculature	Absent		GUDMAP:9128
TS23: renal medullary arterial system	Absent		GUDMAP:9128
TS23: renal medullary venous system	Absent		GUDMAP:9128
TS23: renal medullary capillary	Absent		GUDMAP:9128
TS23: medullary collecting duct	Absent		GUDMAP:9128
TS23: renal calyx	Absent		GUDMAP:9128
TS23: renal pelvis	Absent		GUDMAP:9128
TS23: pelvic urothelial lining	Absent		GUDMAP:9128
TS23: pelvic smooth muscle	Absent		GUDMAP:9128
TS23: perihilar interstitium	Absent		GUDMAP:9128
TS23: developing capillary loop stage nephron group	Absent		GUDMAP:9128
TS23: collecting duct	Absent		GUDMAP:9128
TS23: renal interstitium	Absent		GUDMAP:9128
TS23: renal vasculature	Absent		GUDMAP:9128
TS23: early nephron	Absent		GUDMAP:9128
TS23: cortical early distal tubule	Ambiguous		GUDMAP:9128	uncertain due to inability to identify tubule subtype
TS23: cortical renal tubule of maturing nephron group	Present	Regionally restricted	GUDMAP:9128
TS23: early proximal tubule of maturing nephron	Present	Regionally restricted	GUDMAP:9128	distal expression; expression restricted to a subset of the early proximal; expression absent from first portion of proximal tubule at the urinary pole of the maturing nephron presumptive segment 1
TS23: cortical renal tubule of capillary loop nephron group	Absent		GUDMAP:9128
TS23: early proximal tubule of capillary loop nephron	Absent		GUDMAP:9128
TS23: early distal tubule of capillary loop nephron	Absent		GUDMAP:9128
TS23: renal connecting tubule of capillary loop nephron	Absent		GUDMAP:9128
TS23: renal connecting tubule of maturing nephron	Absent		GUDMAP:9128
TS23: early distal tubule of maturing nephron	Ambiguous		GUDMAP:9128	uncertain due to inability to identify tubule subtype

GUDMAP:9129 ©

Specimen GUDMAP:9129: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Image
TS23: ureter	Absent	GUDMAP:9129
TS23: urothelium of ureter	Absent	GUDMAP:9129
TS23: superficial cell layer of ureter	Absent	GUDMAP:9129
TS23: intermediate cell layer of ureter	Absent	GUDMAP:9129
TS23: basal cell layer of ureter	Absent	GUDMAP:9129
TS23: ureteral mesenchyme	Absent	GUDMAP:9129
TS23: ureteral mesenchyme subepithelial layer	Absent	GUDMAP:9129
TS23: ureteral smooth muscle layer	Absent	GUDMAP:9129
TS23: ureteral smooth muscle layer smooth muscle component	Absent	GUDMAP:9129
TS23: ureteral smooth muscle layer interstitium	Absent	GUDMAP:9129
TS23: ureteral mesenchyme outer layer	Absent	GUDMAP:9129
TS23: ureteral vasculature	Absent	GUDMAP:9129

GUDMAP:13941 ©

Specimen GUDMAP:13941: postnatal adult (more

)
Note: This animal was sexually mature. Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS28: metanephros	Present		GUDMAP:13941
TS28: urinary system	Present		GUDMAP:13941
TS28: renal cortex	Present		GUDMAP:13941
TS28: renal medulla	Present		GUDMAP:13941
TS28: outer renal medulla	Present		GUDMAP:13941
TS28: outer stripe of outer medulla	Present		GUDMAP:13941
TS28: loop of Henle of outer stripe of outer medulla	Present		GUDMAP:13941
TS28: proximal straight tubule of outer stripe of outer medulla	Present		GUDMAP:13941
TS28: distal straight tubule of outer stripe of outer medulla	Absent		GUDMAP:13941
TS28: inner stripe of outer medulla	Absent		GUDMAP:13941
TS28: outer medullary collecting duct	Absent		GUDMAP:13941
TS28: inner renal medulla	Absent		GUDMAP:13941
TS28: renal pelvis	Absent		GUDMAP:13941
TS28: mature renal corpuscle	Absent		GUDMAP:13941
TS28: cortical collecting duct	Absent		GUDMAP:13941
TS28: renal cortical interstitium	Absent		GUDMAP:13941
TS28: renal cortical vasculature	Absent		GUDMAP:13941
TS28: cortical renal tubule	Present		GUDMAP:13941
TS28: loop of Henle, outer medullary portion	Present		GUDMAP:13941
TS28: proximal straight tubule, outer medullary portion	Present		GUDMAP:13941
TS28: renal proximal tubule	Present	Regionally restricted	GUDMAP:13941	graded expression
TS28: renal proximal convoluted tubule	Present	Regionally restricted	GUDMAP:13941	graded expression; Strong expression detected in segment 2 and weaker expression in proximal straight tubule (segment 3). Expression absent from segment 1 immediately adjacent to the renal corpuscle.
TS28: proximal straight tubule, cortical portion	Present		GUDMAP:13941
TS28: segment 2 of proximal tubule	Present		GUDMAP:13941
TS28: segment 1 of proximal tubule	Ambiguous		GUDMAP:13941
TS28: renal distal tubule	Absent		GUDMAP:13941
TS28: renal connecting tubule	Absent		GUDMAP:13941
TS28: outer medullary interstitium	Absent		GUDMAP:13941
TS28: renal medullary vasculature	Absent		GUDMAP:13941
TS28: premacula segment of distal straight tubule of outer medulla	Absent		GUDMAP:13941
TS28: thin ascending limb of outer medulla	Absent		GUDMAP:13941
TS28: thin descending limb of outer medulla	Absent		GUDMAP:13941

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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