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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541687
Gene symbol: Cgref1
Gene name: cell growth regulator with EF hand domain 1
Probe: RIKEN clone 1110004G24 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:9053: embryonic day 15.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:9053
TS23: metanephros Present Regionally restricted GUDMAP:9053
TS23: late tubule Present GUDMAP:9053
TS23: renal cortex Present GUDMAP:9053
TS23: renal medulla Present GUDMAP:9053
TS23: renal pelvis Present GUDMAP:9053
TS23: ureter Present GUDMAP:9053
TS23: urothelium of ureter Present GUDMAP:9053
TS23: renal capsule Absent GUDMAP:9053
TS23: cap mesenchyme Absent GUDMAP:9053
TS23: ureteric tip Absent GUDMAP:9053
TS23: early nephron Absent GUDMAP:9053
TS23: nephrogenic zone Absent GUDMAP:9053 signal seen in the nephrogenic zone is background staining
Specimen GUDMAP:9054: embryonic day 15.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:9054
TS23: bladder Present GUDMAP:9054
TS23: urothelium of bladder Present GUDMAP:9054
Specimen GUDMAP:9172: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: urinary system Present Regionally restricted GUDMAP:9172
TS28: metanephros Present Regionally restricted GUDMAP:9172
TS28: renal cortex Present Regionally restricted GUDMAP:9172
TS28: cortical renal tubule Present Regionally restricted GUDMAP:9172
TS28: renal proximal tubule Present Regionally restricted GUDMAP:9172
TS28: renal proximal convoluted tubule Present Regionally restricted GUDMAP:9172 expression in a subset of proximal convoluted tubules of cortex which includes S2 and S3 and maybe S1 although the first portion of S1 adjacent to the renal corpuscle is absent
TS28: proximal straight tubule, cortical portion Present GUDMAP:9172
TS28: renal medulla Present Regionally restricted GUDMAP:9172
TS28: outer renal medulla Present Regionally restricted GUDMAP:9172
TS28: outer stripe of outer medulla Present Regionally restricted GUDMAP:9172
TS28: loop of Henle, outer medullary portion Present GUDMAP:9172
TS28: proximal straight tubule, outer medullary portion Present GUDMAP:9172
TS28: segment 2 of proximal tubule Present GUDMAP:9172 expression possibly in a subset of segment 2
TS28: mature renal corpuscle Absent GUDMAP:9172
TS28: glomerular tuft Absent GUDMAP:9172
TS28: glomerular capillary system Absent GUDMAP:9172
TS28: glomerular mesangium of glomerular tuft Absent GUDMAP:9172
TS28: glomerular basement membrane of mature renal corpuscle Absent GUDMAP:9172
TS28: visceral epithelium of mature renal corpuscle Absent GUDMAP:9172
TS28: Bowman's capsule of mature renal corpuscle Absent GUDMAP:9172
TS28: parietal epithelium of mature renal corpuscle Absent GUDMAP:9172
TS28: urinary space of mature renal corpuscle Absent GUDMAP:9172
TS28: afferent arteriole of mature renal corpuscle Absent GUDMAP:9172
TS28: part of afferent arteriole forming the juxtaglomerular complex Absent GUDMAP:9172
TS28: rest of afferent arteriole Absent GUDMAP:9172
TS28: efferent arteriole of mature renal corpuscle Absent GUDMAP:9172
TS28: extraglomerular mesangium Absent GUDMAP:9172
TS28: renal connecting tubule Absent GUDMAP:9172
TS28: cortical collecting duct Absent GUDMAP:9172
TS28: renal cortical vasculature Absent GUDMAP:9172
TS28: renal cortical arterial system Absent GUDMAP:9172
TS28: interlobular artery Absent GUDMAP:9172
TS28: arcuate artery Absent GUDMAP:9172
TS28: renal cortical venous system Absent GUDMAP:9172
TS28: interlobular vein Absent GUDMAP:9172
TS28: arcuate vein Absent GUDMAP:9172
TS28: renal cortical capillary Absent GUDMAP:9172
TS28: inner stripe of outer medulla Absent GUDMAP:9172
TS28: loop of Henle of inner stripe of outer medulla Absent GUDMAP:9172
TS28: thin descending limb of inner stripe of outer medulla Absent GUDMAP:9172
TS28: premacula segment of distal straight tubule of inner stripe of inner medulla Absent GUDMAP:9172
TS28: outer medullary collecting duct Absent GUDMAP:9172
TS28: outer medullary interstitium Absent GUDMAP:9172
TS28: inner renal medulla Absent GUDMAP:9172
TS28: loop of Henle, inner medullary portion Absent GUDMAP:9172
TS28: inner medullary collecting duct Absent GUDMAP:9172
TS28: inner medullary interstitium Absent GUDMAP:9172
TS28: renal medullary vasculature Absent GUDMAP:9172
TS28: renal medullary arterial system Absent GUDMAP:9172
TS28: renal medullary venous system Absent GUDMAP:9172
TS28: renal medullary capillary Absent GUDMAP:9172
TS28: renal pelvis Absent GUDMAP:9172
TS28: pelvic urothelial lining Absent GUDMAP:9172
TS28: pelvic smooth muscle Absent GUDMAP:9172
TS28: perihilar interstitium Absent GUDMAP:9172
TS28: segment 1 of proximal tubule Ambiguous GUDMAP:9172 expression absent from the first portion of segment 1 adjacent to the renal corpuscle but it is unknown if expression is present in the remainder of segment 1
TS28: renal distal tubule Ambiguous GUDMAP:9172 possible expression in distal convoluted tubule
TS28: distal convoluted tubule Ambiguous GUDMAP:9172 possible expression
Specimen GUDMAP:9173: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present Regionally restricted GUDMAP:9173
TS23: metanephros Present Regionally restricted GUDMAP:9173
TS23: renal cortex Present Regionally restricted GUDMAP:9173
TS23: cortical renal tubule Present Regionally restricted GUDMAP:9173 strong regional expression in a subset of tubules which included early proximal and may include distal. Weaker expression in capillary loop nephron tubules
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:9173 regional expression. The first portion of tubule (presumptive segment 1) adjacent to the renal corpuscle appears to be absent from expression
TS23: developing capillary loop stage nephron group Present GUDMAP:9173
TS23: maturing nephron Present Regionally restricted GUDMAP:9173
TS23: late tubule Present Regionally restricted GUDMAP:9173
TS23: renal medulla Present Regionally restricted GUDMAP:9173
TS23: immature loop of Henle Present GUDMAP:9173 weak expression
TS23: renal capsule Absent GUDMAP:9173
TS23: nephrogenic zone Absent GUDMAP:9173
TS23: nephrogenic interstitium Absent GUDMAP:9173
TS23: cap mesenchyme Absent GUDMAP:9173
TS23: pretubular aggregate Absent GUDMAP:9173
TS23: ureteric tip Absent GUDMAP:9173
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:9173
TS23: renal vesicle Absent GUDMAP:9173
TS23: comma-shaped body Absent GUDMAP:9173
TS23: upper limb of comma-shaped body Absent GUDMAP:9173
TS23: lower limb of comma-shaped body Absent GUDMAP:9173
TS23: s-shaped body Absent GUDMAP:9173
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:9173
TS23: distal segment of s-shaped body Absent GUDMAP:9173
TS23: medial segment of s-shaped body Absent GUDMAP:9173
TS23: proximal segment of s-shaped body Absent GUDMAP:9173
TS23: visceral epithelium of s-shaped body Absent GUDMAP:9173
TS23: parietal epithelium of s-shaped body Absent GUDMAP:9173
TS23: capillary loop renal corpuscle Absent GUDMAP:9173
TS23: visceral epithelium of capillary loop renal corpuscle Absent GUDMAP:9173
TS23: parietal epithelium of capillary loop renal corpuscle Absent GUDMAP:9173
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:9173
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:9173
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:9173
TS23: maturing renal corpuscle Absent GUDMAP:9173
TS23: maturing glomerular tuft Absent GUDMAP:9173
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:9173
TS23: glomerular basement membrane of maturing renal corpuscle Absent GUDMAP:9173
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:9173
TS23: visceral epithelium of maturing renal corpuscle Absent GUDMAP:9173
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:9173
TS23: parietal epithelium of maturing renal corpuscle Absent GUDMAP:9173
TS23: glomerular mesangium of maturing renal corpuscle Absent GUDMAP:9173
TS23: juxtaglomerular arteriole Absent GUDMAP:9173
TS23: collecting duct Absent GUDMAP:9173
TS23: renal interstitium Absent GUDMAP:9173
TS23: renal vasculature Absent GUDMAP:9173
TS23: early nephron Absent GUDMAP:9173
TS23: cortical collecting duct Absent GUDMAP:9173
TS23: renal cortical interstitium Absent GUDMAP:9173
TS23: renal cortical vasculature Absent GUDMAP:9173
TS23: renal cortical arterial system Absent GUDMAP:9173
TS23: renal cortical venous system Absent GUDMAP:9173
TS23: renal cortical capillary Absent GUDMAP:9173
TS23: renal connecting tubule Absent GUDMAP:9173
TS23: renal medullary interstitium Absent GUDMAP:9173
TS23: renal medullary vasculature Absent GUDMAP:9173
TS23: renal medullary arterial system Absent GUDMAP:9173
TS23: renal medullary venous system Absent GUDMAP:9173
TS23: renal medullary capillary Absent GUDMAP:9173
TS23: medullary collecting duct Absent GUDMAP:9173
TS23: renal calyx Absent GUDMAP:9173
TS23: renal pelvis Absent GUDMAP:9173
TS23: pelvic urothelial lining Absent GUDMAP:9173
TS23: pelvic smooth muscle Absent GUDMAP:9173
TS23: perihilar interstitium Absent GUDMAP:9173
TS23: cortical early distal tubule Ambiguous GUDMAP:9173 possible expression but distal tubules are difficult to identify
TS23: anlage of loop of Henle of cortical renal tubule Ambiguous GUDMAP:9173 possible expression
TS23: cortical renal tubule of capillary loop nephron group Present Regionally restricted GUDMAP:9173
TS23: cortical renal tubule of maturing nephron group Present Regionally restricted GUDMAP:9173
TS23: early proximal tubule of maturing nephron Present Regionally restricted GUDMAP:9173
TS23: renal connecting segment of comma-shaped body Absent GUDMAP:9173
TS23: renal connecting tubule of maturing nephron Absent GUDMAP:9173
TS23: early distal tubule of capillary loop nephron Ambiguous GUDMAP:9173
TS23: early distal tubule of maturing nephron Ambiguous GUDMAP:9173 possible expression but distal tubules are difficult to identify
TS23: early proximal tubule of capillary loop nephron Ambiguous GUDMAP:9173
Specimen GUDMAP:9174: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Absent GUDMAP:9174
TS23: urothelium of ureter Absent GUDMAP:9174
TS23: superficial cell layer of ureter Absent GUDMAP:9174
TS23: intermediate cell layer of ureter Absent GUDMAP:9174
TS23: basal cell layer of ureter Absent GUDMAP:9174
TS23: ureteral mesenchyme Absent GUDMAP:9174
TS23: ureteral mesenchyme subepithelial layer Absent GUDMAP:9174
TS23: ureteral smooth muscle layer Absent GUDMAP:9174
TS23: ureteral smooth muscle layer smooth muscle component Absent GUDMAP:9174
TS23: ureteral smooth muscle layer interstitium Absent GUDMAP:9174
TS23: ureteral mesenchyme outer layer Absent GUDMAP:9174
TS23: ureteral vasculature Absent GUDMAP:9174
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory