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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5541554
Gene symbol: Greb1
Gene name: gene regulated by estrogen in breast cancer protein
Probe: RIKEN clone 5730583K22 subclone 1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7777: embryonic day 10.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7777 ubiquitous expression
TS17: mesonephros Present GUDMAP:7777
TS17: metanephric mesenchyme Present GUDMAP:7777
TS17: nephric duct, metanephric portion Present GUDMAP:7777
TS17: mesonephric tubule Present GUDMAP:7777 strongest signal in most rostral mesonephric glomerulus
TS17: mesonephros mesenchyme Present GUDMAP:7777
TS17: cranial mesonephric tubule Present GUDMAP:7777
TS17: caudal mesonephric tubule Ambiguous GUDMAP:7777
TS17: rest of cranial mesonephric tubule Present GUDMAP:7777
Specimen GUDMAP:7778: embryonic day 12.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7778
TS20: metanephros Present GUDMAP:7778
TS20: early nephron Present GUDMAP:7778 strongest expression
TS20: urogenital mesentery Present GUDMAP:7778
TS20: ureteric tip Present GUDMAP:7778 moderate expression
Specimen GUDMAP:7779: embryonic day 12.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: female reproductive system Present GUDMAP:7779
TS20: ovary Present GUDMAP:7779
TS20: mesonephros of female Present GUDMAP:7779
TS20: mesonephric mesenchyme of female Present GUDMAP:7779
TS20: paramesonephric duct of female, mesonephric portion Present GUDMAP:7779 signal may be stronger in the caudal end of the duct
TS20: nephric duct of female, mesonephric portion Present GUDMAP:7779
TS20: urogenital mesentery Present GUDMAP:7779
Specimen GUDMAP:8891: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: metanephros Present Regionally restricted GUDMAP:8891
TS23: nephrogenic zone Present Regionally restricted GUDMAP:8891
TS23: ureteric tip Present Regionally restricted GUDMAP:8891 weak expression restricted to subset of ureteric tips
TS23: pretubular aggregate Present GUDMAP:8891
TS23: renal vesicle Present Regionally restricted GUDMAP:8891 distal expression; signal restricted to distal renal vesicle adjacent to ureteric tip
TS23: comma-shaped body Present Regionally restricted GUDMAP:8891
TS23: upper limb of comma-shaped body Present GUDMAP:8891
TS23: s-shaped body Present Regionally restricted GUDMAP:8891
TS23: medial segment of s-shaped body Present GUDMAP:8891
TS23: cortical renal tubule Present Regionally restricted GUDMAP:8891 signal restricted to early proximal tubule of capillary loop nephrons
TS23: developing capillary loop stage nephron group Present Regionally restricted GUDMAP:8891 signal restricted to early proximal tubule
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:8891
TS23: renal capsule Absent GUDMAP:8891
TS23: nephrogenic interstitium Absent GUDMAP:8891
TS23: cap mesenchyme Absent GUDMAP:8891
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8891
TS23: capillary loop renal corpuscle Absent GUDMAP:8891
TS23: maturing renal corpuscle Absent GUDMAP:8891
TS23: maturing nephron Absent GUDMAP:8891
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:8891
TS23: cortical early distal tubule Absent GUDMAP:8891
TS23: renal connecting tubule Absent GUDMAP:8891
TS23: renal medulla Absent GUDMAP:8891
TS23: renal pelvis Absent GUDMAP:8891
TS23: ureter Absent GUDMAP:8891
TS23: lower limb of comma-shaped body Absent GUDMAP:8891
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8891 expression absent from connecting tubules of comma- and S-shaped bodies
TS23: distal segment of s-shaped body Absent GUDMAP:8891
TS23: proximal segment of s-shaped body Absent GUDMAP:8891
TS23: visceral epithelium of s-shaped body Absent GUDMAP:8891
TS23: parietal epithelium of s-shaped body Absent GUDMAP:8891
TS23: distal renal vesicle Present GUDMAP:8891
TS23: cortical renal tubule of capillary loop nephron group Present GUDMAP:8891
TS23: early proximal tubule of capillary loop nephron Present GUDMAP:8891
TS23: cortical renal tubule of maturing nephron group Absent GUDMAP:8891
Specimen GUDMAP:8892: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. This assay's probe was visualized using BM purple; it is blue. The section was also subjected to immunohistochemistry with an anti-Calb1 antibody to detect the primitive collecting duct (including ureteric tips); that labeling is orange.
Structure Level Pattern Image Note
TS23: metanephros Present Regionally restricted GUDMAP:8892
TS23: nephrogenic zone Present Regionally restricted GUDMAP:8892
TS23: ureteric tip Present Regionally restricted GUDMAP:8892 weak expression restricted to subset of ureteric tips
TS23: pretubular aggregate Present GUDMAP:8892
TS23: renal vesicle Present Regionally restricted GUDMAP:8892 distal expression; signal restricted to distal renal vesicle adjacent to ureteric tip
TS23: comma-shaped body Present Regionally restricted GUDMAP:8892
TS23: upper limb of comma-shaped body Present GUDMAP:8892
TS23: s-shaped body Present Regionally restricted GUDMAP:8892
TS23: medial segment of s-shaped body Present GUDMAP:8892
TS23: cortical renal tubule Present Regionally restricted GUDMAP:8892 signal restricted to early proximal tubule of capillary loop nephrons
TS23: developing capillary loop stage nephron group Present Regionally restricted GUDMAP:8892 signal restricted to early proximal tubule
TS23: renal capsule Absent GUDMAP:8892
TS23: nephrogenic interstitium Absent GUDMAP:8892
TS23: cap mesenchyme Absent GUDMAP:8892
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:8892
TS23: capillary loop renal corpuscle Absent GUDMAP:8892
TS23: maturing renal corpuscle Absent GUDMAP:8892
TS23: maturing nephron Absent GUDMAP:8892
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:8892
TS23: cortical early distal tubule Absent GUDMAP:8892
TS23: renal connecting tubule Absent GUDMAP:8892
TS23: renal medulla Absent GUDMAP:8892
TS23: renal pelvis Absent GUDMAP:8892
TS23: ureter Absent GUDMAP:8892
TS23: lower limb of comma-shaped body Absent GUDMAP:8892
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:8892 expression absent from connecting tubules of comma- and S-shaped bodies
TS23: distal segment of s-shaped body Absent GUDMAP:8892
TS23: proximal segment of s-shaped body Absent GUDMAP:8892
TS23: visceral epithelium of s-shaped body Absent GUDMAP:8892
TS23: parietal epithelium of s-shaped body Absent GUDMAP:8892
TS23: distal renal vesicle Present GUDMAP:8892
TS23: cortical renal tubule of capillary loop nephron group Present GUDMAP:8892
TS23: cortical renal tubule of maturing nephron group Absent GUDMAP:8892
Specimen GUDMAP:8893: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Absent GUDMAP:8893
Specimen GUDMAP:8959: embryonic day 15.5 (more )
Note: This specimen was generated and annotated by the lab of Melissa H. Little, Murdoch Children's Research Institute. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: ureter Absent GUDMAP:8959
TS23: urothelium of ureter Absent GUDMAP:8959
TS23: ureteral mesenchyme Absent GUDMAP:8959
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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