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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540882
Gene symbol: Tcn2
Gene name: transcobalamin 2
Probe: RIKEN clone F430103L11 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:9178: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present Regionally restricted GUDMAP:9178
TS23: metanephros Present Regionally restricted GUDMAP:9178
TS23: renal cortex Present Regionally restricted GUDMAP:9178
TS23: cortical renal tubule Present Regionally restricted GUDMAP:9178 strong expression in subset of tubules of maturing nephrons only including early proximal and expression detected in tubules adjacent to immature loop of Henle
TS23: cortical early proximal tubule Present Regionally restricted GUDMAP:9178 expression restricted to early proximal of maturing nephrons only and expression detected in tubules adjacent to immature loop of Henle
TS23: maturing nephron Present Regionally restricted GUDMAP:9178
TS23: late tubule Present Regionally restricted GUDMAP:9178
TS23: renal capsule Absent GUDMAP:9178
TS23: nephrogenic zone Absent GUDMAP:9178
TS23: nephrogenic interstitium Absent GUDMAP:9178
TS23: cap mesenchyme Absent GUDMAP:9178
TS23: pretubular aggregate Absent GUDMAP:9178
TS23: ureteric tip Absent GUDMAP:9178
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:9178
TS23: renal vesicle Absent GUDMAP:9178
TS23: comma-shaped body Absent GUDMAP:9178
TS23: upper limb of comma-shaped body Absent GUDMAP:9178
TS23: lower limb of comma-shaped body Absent GUDMAP:9178
TS23: s-shaped body Absent GUDMAP:9178
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:9178
TS23: distal segment of s-shaped body Absent GUDMAP:9178
TS23: medial segment of s-shaped body Absent GUDMAP:9178
TS23: proximal segment of s-shaped body Absent GUDMAP:9178
TS23: visceral epithelium of s-shaped body Absent GUDMAP:9178
TS23: parietal epithelium of s-shaped body Absent GUDMAP:9178
TS23: capillary loop renal corpuscle Absent GUDMAP:9178
TS23: visceral epithelium of capillary loop renal corpuscle Absent GUDMAP:9178
TS23: parietal epithelium of capillary loop renal corpuscle Absent GUDMAP:9178
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:9178
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:9178
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:9178
TS23: maturing renal corpuscle Absent GUDMAP:9178
TS23: maturing glomerular tuft Absent GUDMAP:9178
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:9178
TS23: glomerular basement membrane of maturing renal corpuscle Absent GUDMAP:9178
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:9178
TS23: visceral epithelium of maturing renal corpuscle Absent GUDMAP:9178
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:9178
TS23: parietal epithelium of maturing renal corpuscle Absent GUDMAP:9178
TS23: glomerular mesangium of maturing renal corpuscle Absent GUDMAP:9178
TS23: juxtaglomerular arteriole Absent GUDMAP:9178
TS23: anlage of loop of Henle of cortical renal tubule Absent GUDMAP:9178
TS23: cortical collecting duct Absent GUDMAP:9178
TS23: renal cortical interstitium Absent GUDMAP:9178
TS23: renal cortical vasculature Absent GUDMAP:9178
TS23: renal cortical arterial system Absent GUDMAP:9178
TS23: renal cortical venous system Absent GUDMAP:9178
TS23: renal cortical capillary Absent GUDMAP:9178
TS23: renal connecting tubule Absent GUDMAP:9178
TS23: renal medulla Absent GUDMAP:9178
TS23: immature loop of Henle Absent GUDMAP:9178
TS23: straight limb of immature loop of Henle Absent GUDMAP:9178
TS23: bend of immature loop of Henle Absent GUDMAP:9178
TS23: renal medullary interstitium Absent GUDMAP:9178
TS23: renal medullary vasculature Absent GUDMAP:9178
TS23: renal medullary arterial system Absent GUDMAP:9178
TS23: renal medullary venous system Absent GUDMAP:9178
TS23: renal medullary capillary Absent GUDMAP:9178
TS23: medullary collecting duct Absent GUDMAP:9178
TS23: renal calyx Absent GUDMAP:9178
TS23: renal pelvis Absent GUDMAP:9178
TS23: pelvic urothelial lining Absent GUDMAP:9178
TS23: pelvic smooth muscle Absent GUDMAP:9178
TS23: perihilar interstitium Absent GUDMAP:9178
TS23: developing capillary loop stage nephron group Absent GUDMAP:9178
TS23: collecting duct Absent GUDMAP:9178
TS23: renal interstitium Absent GUDMAP:9178
TS23: renal vasculature Absent GUDMAP:9178
TS23: early nephron Absent GUDMAP:9178
TS23: cortical early distal tubule Ambiguous GUDMAP:9178 uncertain due to inability to identify tubule subtype
TS23: cortical renal tubule of maturing nephron group Present Regionally restricted GUDMAP:9178
TS23: early proximal tubule of maturing nephron Present GUDMAP:9178
TS23: cortical renal tubule of capillary loop nephron group Absent GUDMAP:9178
TS23: early proximal tubule of capillary loop nephron Absent GUDMAP:9178
TS23: early distal tubule of capillary loop nephron Absent GUDMAP:9178
TS23: renal connecting tubule of capillary loop nephron Absent GUDMAP:9178
TS23: renal connecting tubule of maturing nephron Absent GUDMAP:9178
TS23: early distal tubule of maturing nephron Ambiguous GUDMAP:9178 uncertain due to inability to identify tubule subtype
Specimen GUDMAP:9504: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:9504
TS17: genitourinary system mesenchyme Present GUDMAP:9504
TS17: mesonephros Present GUDMAP:9504
TS17: mesonephros mesenchyme Present GUDMAP:9504
TS17: metanephric mesenchyme Present GUDMAP:9504
TS17: mesonephric tubule Ambiguous GUDMAP:9504
TS17: nephric duct, mesonephric portion Ambiguous GUDMAP:9504
TS17: nephric duct, metanephric portion Ambiguous GUDMAP:9504
TS17: nephric duct Ambiguous GUDMAP:9504
Specimen GUDMAP:9505: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present Regionally restricted GUDMAP:9505
TS21: mesonephros of male Present Regionally restricted GUDMAP:9505
TS21: mesonephric mesenchyme of male Present GUDMAP:9505 weak signal detected
TS21: mesonephric tubule of male Present GUDMAP:9505
TS21: testis Present Regionally restricted GUDMAP:9505
TS21: primary sex cord Present GUDMAP:9505
TS21: nephric duct of male, mesonephric portion Absent GUDMAP:9505
TS21: paramesonephric duct of male, mesonephric portion Absent GUDMAP:9505
TS21: nephric duct of male, rest of Absent GUDMAP:9505
TS21: epithelium of nephric duct of male Absent GUDMAP:9505
TS21: paramesonephric duct of male, rest of Absent GUDMAP:9505
TS21: epithelium of rest of paramesonephric duct of male Absent GUDMAP:9505
TS21: interstitium of the testis Absent GUDMAP:9505
TS21: developing vasculature of testis Ambiguous GUDMAP:9505
TS21: coelomic epithelium of testis Ambiguous GUDMAP:9505
TS21: coelomic epithelium of male mesonephros Ambiguous GUDMAP:9505
TS21: mesenchyme of nephric duct of male Ambiguous GUDMAP:9505
TS21: mesenchyme of rest of paramesonephric duct of male Ambiguous GUDMAP:9505
Specimen GUDMAP:9506: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9506
TS21: metanephros Present GUDMAP:9506
TS21: renal interstitium Present GUDMAP:9506 possible expression; strongest signal detected in what appears to be the interstitium
Specimen GUDMAP:9507: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9507
TS21: urogenital sinus Present GUDMAP:9507
TS21: primitive bladder Present GUDMAP:9507
Specimen GUDMAP:9508: embryonic day 13.0 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: female reproductive system Present Regionally restricted GUDMAP:9508
TS21: mesonephros of female Present Regionally restricted GUDMAP:9508
TS21: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:9508 signal is absent from the mesenchyme surrounding the paramesonephric duct mesonephric portion
TS21: mesonephric tubule of female Present GUDMAP:9508
TS21: ovary Present Regionally restricted GUDMAP:9508
TS21: mesenchymal stroma of ovary Present GUDMAP:9508
TS21: nephric duct of female, mesonephric portion Absent GUDMAP:9508
TS21: paramesonephric duct of female, mesonephric portion Absent GUDMAP:9508
TS21: coelomic epithelium of female mesonephros Absent GUDMAP:9508
TS21: nephric duct of female, rest of Absent GUDMAP:9508
TS21: epithelium of nephric duct of female Absent GUDMAP:9508
TS21: paramesonephric duct of female, rest of Absent GUDMAP:9508
TS21: epithelium of rest of paramesonephric duct of female Absent GUDMAP:9508
TS21: mesenchyme of rest of paramesonephric duct of female Ambiguous GUDMAP:9508
TS21: mesenchyme of nephric duct of female Ambiguous GUDMAP:9508
Specimen GUDMAP:9509: embryonic day 13.0 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9509
TS21: metanephros Present GUDMAP:9509
TS21: renal interstitium Present GUDMAP:9509 possible expression; strongest signal detected in what appears to be the interstitium
Specimen GUDMAP:9510: embryonic day 13.0 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9510
TS21: urogenital sinus Present GUDMAP:9510
TS21: primitive bladder Present GUDMAP:9510
Specimen GUDMAP:10922: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: urinary system Present GUDMAP:10922
TS28: metanephros Present Regionally restricted GUDMAP:10922
TS28: renal cortex Present Regionally restricted GUDMAP:10922
TS28: cortical renal tubule Present Regionally restricted GUDMAP:10922
TS28: renal proximal tubule Present Regionally restricted GUDMAP:10922
TS28: renal proximal convoluted tubule Present Regionally restricted GUDMAP:10922 expression absent from a small subset of renal proximal convoluted tubules
TS28: segment 1 of proximal tubule Present GUDMAP:10922
TS28: segment 2 of proximal tubule Present GUDMAP:10922
TS28: proximal straight tubule, cortical portion Present GUDMAP:10922
TS28: renal medulla Present Regionally restricted GUDMAP:10922
TS28: outer renal medulla Present Regionally restricted GUDMAP:10922
TS28: outer stripe of outer medulla Present Regionally restricted GUDMAP:10922
TS28: loop of Henle of outer stripe of outer medulla Present Regionally restricted GUDMAP:10922
TS28: proximal straight tubule of outer stripe of outer medulla Present Regionally restricted GUDMAP:10922 graded expression; regional expression in a subset of S3 with weak expression in some S3
TS28: mature renal corpuscle Absent GUDMAP:10922
TS28: renal distal tubule Absent GUDMAP:10922
TS28: renal connecting tubule Absent GUDMAP:10922
TS28: cortical collecting duct Absent GUDMAP:10922
TS28: renal cortical interstitium Absent GUDMAP:10922
TS28: renal cortical vasculature Absent GUDMAP:10922
TS28: inner renal medulla Absent GUDMAP:10922
TS28: renal pelvis Absent GUDMAP:10922
TS28: distal straight tubule of outer stripe of outer medulla Absent GUDMAP:10922
TS28: inner stripe of outer medulla Absent GUDMAP:10922
TS28: outer medullary collecting duct Absent GUDMAP:10922
TS28: outer medullary interstitium Absent GUDMAP:10922
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory