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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540867
Gene symbol: Hoxa10
Gene name: homeobox A10
Probe: RIKEN clone 0610025N02 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:8842: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:8842
TS17: mesonephros Present Regionally restricted GUDMAP:8842 caudal expression
TS17: mesonephros mesenchyme Present Regionally restricted GUDMAP:8842 caudal expression; signal absent from the rostral mesonephros
TS17: metanephric mesenchyme Present GUDMAP:8842
TS17: genitourinary system mesenchyme Absent GUDMAP:8842
TS17: gonad primordium Absent GUDMAP:8842
TS17: mesonephric tubule Absent GUDMAP:8842
TS17: nephric duct, mesonephric portion Absent GUDMAP:8842
TS17: nephric duct, metanephric portion Absent GUDMAP:8842
TS17: nephric duct Absent GUDMAP:8842
Specimen GUDMAP:8843: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: male reproductive system Present Regionally restricted GUDMAP:8843
TS20: mesonephros of male Present Regionally restricted GUDMAP:8843 caudal expression
TS20: nephric duct of male, mesonephric portion Absent GUDMAP:8843 signal is in the mesenchyme surrounding the duct epithelium in the caudal mesonephros only
TS20: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:8843 caudal expression; restricted signal pattern in the caudal mesonephros and surrounding the duct epithelia
TS20: mesonephric tubule of male Absent GUDMAP:8843
TS20: paramesonephric duct of male, mesonephric portion Absent GUDMAP:8843 signal is in the mesenchyme surrounding the duct epithelium in the caudal mesonephros only
TS20: coelomic epithelium of male mesonephros Absent GUDMAP:8843
TS20: paramesonephric duct of male, rest of Present Regionally restricted GUDMAP:8843 Expression present in the caudal mesenchyme surrounding the epithelia of the paramesonephric and nephric ducts.
TS20: nephric duct of male, rest of Present Regionally restricted GUDMAP:8843 Expression present in the caudal mesenchyme surrounding the epithelia of the paramesonephric and nephric ducts.
TS20: testis Present Regionally restricted GUDMAP:8843
TS20: primary sex cord Present GUDMAP:8843
Specimen GUDMAP:8844: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present Regionally restricted GUDMAP:8844
TS20: urogenital mesentery Present GUDMAP:8844
TS20: metanephros Present Regionally restricted GUDMAP:8844
TS20: ureter Ambiguous GUDMAP:8844
TS20: nephrogenic interstitium Present GUDMAP:8844
TS20: cap mesenchyme Present GUDMAP:8844
TS20: pretubular aggregate Ambiguous GUDMAP:8844
TS20: renal interstitium Present GUDMAP:8844 possible expression; structure is masked by strong signal on surface of metanephros
TS20: early nephron Present GUDMAP:8844
TS20: nephrogenic zone Present Regionally restricted GUDMAP:8844
TS20: ureteric tip Absent GUDMAP:8844
Specimen GUDMAP:8845: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:8845
TS21: urogenital sinus Present GUDMAP:8845
TS21: primitive bladder Present GUDMAP:8845 signal appears strongest in the rostral bladder
TS21: urothelium of primitive bladder Present GUDMAP:8845
TS21: mesenchymal layer of primitive bladder Present GUDMAP:8845
Specimen GUDMAP:8846: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: female reproductive system Present Regionally restricted GUDMAP:8846
TS20: mesonephros of female Present Regionally restricted GUDMAP:8846
TS20: paramesonephric duct of female, rest of Present Regionally restricted GUDMAP:8846 Expression present in the caudal mesenchyme surrounding the epithelia of the paramesonephric and nephric ducts.
TS20: nephric duct of female, rest of Present Regionally restricted GUDMAP:8846 Expression present in the caudal mesenchyme surrounding the epithelia of the paramesonephric and nephric ducts.
TS20: ovary Absent GUDMAP:8846
TS20: coelomic epithelium of female mesonephros Absent GUDMAP:8846
TS20: paramesonephric duct of female, mesonephric portion Absent GUDMAP:8846 signal is in the mesenchyme surrounding the duct epithelium in the caudal mesonephros only
TS20: nephric duct of female, mesonephric portion Absent GUDMAP:8846 signal is in the mesenchyme surrounding the duct epithelium in the caudal mesonephros only
TS20: mesonephric tubule of female Absent GUDMAP:8846
TS20: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:8846 caudal expression
Specimen GUDMAP:8847: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present Regionally restricted GUDMAP:8847
TS20: urogenital mesentery Present GUDMAP:8847
TS20: metanephros Present Regionally restricted GUDMAP:8847
TS20: nephrogenic interstitium Present GUDMAP:8847
TS20: cap mesenchyme Present GUDMAP:8847
TS20: pretubular aggregate Ambiguous GUDMAP:8847 expression is likely to extend into the pretubular aggregates
TS20: renal vesicle Ambiguous GUDMAP:8847 expression seen in early nephrons may be renal vesicles
TS20: early nephron Present GUDMAP:8847
TS20: nephrogenic zone Present Regionally restricted GUDMAP:8847
TS20: renal interstitium Present GUDMAP:8847
TS20: ureter Ambiguous GUDMAP:8847
TS20: ureteric tip Absent GUDMAP:8847
Specimen GUDMAP:8848: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present Regionally restricted GUDMAP:8848
TS21: urogenital sinus Present GUDMAP:8848
TS21: primitive bladder Present GUDMAP:8848
Specimen GUDMAP:9746: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urinary system Present GUDMAP:9746
TS23: metanephros Present Regionally restricted GUDMAP:9746
TS23: nephrogenic zone Present Regionally restricted GUDMAP:9746
TS23: nephrogenic interstitium Present GUDMAP:9746 moderate expression
TS23: cap mesenchyme Present GUDMAP:9746 moderate expression
TS23: pretubular aggregate Present GUDMAP:9746
TS23: ureteric tip Present Regionally restricted GUDMAP:9746 regional strong expression in portion of ureteric tip adjacent to renal connecting tubule
TS23: renal cortex Present Regionally restricted GUDMAP:9746
TS23: s-shaped body Present Regionally restricted GUDMAP:9746
TS23: renal connecting tubule of s-shaped body Present GUDMAP:9746
TS23: distal segment of s-shaped body Present GUDMAP:9746
TS23: cortical renal tubule Present Regionally restricted GUDMAP:9746
TS23: cortical early distal tubule Present GUDMAP:9746 strong expression
TS23: renal connecting tubule Present GUDMAP:9746 strong expression
TS23: renal cortical interstitium Present GUDMAP:9746 weak expression
TS23: renal medulla Present Regionally restricted GUDMAP:9746
TS23: immature loop of Henle Present GUDMAP:9746 weak expression
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:9746 weak expression surrounding collecting ducts and immature loop of Henle
TS23: renal pelvis Present Regionally restricted GUDMAP:9746
TS23: pelvic smooth muscle Present GUDMAP:9746 weak expression
TS23: developing capillary loop stage nephron group Present GUDMAP:9746
TS23: maturing nephron Present GUDMAP:9746
TS23: collecting duct Present GUDMAP:9746
TS23: renal interstitium Present GUDMAP:9746
TS23: early nephron Present GUDMAP:9746
TS23: late tubule Present GUDMAP:9746
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:9746
TS23: medial segment of s-shaped body Absent GUDMAP:9746
TS23: proximal segment of s-shaped body Absent GUDMAP:9746
TS23: capillary loop renal corpuscle Absent GUDMAP:9746
TS23: maturing renal corpuscle Absent GUDMAP:9746
TS23: cortical early proximal tubule Absent GUDMAP:9746
TS23: cortical collecting duct Absent GUDMAP:9746
TS23: renal cortical vasculature Absent GUDMAP:9746
TS23: renal medullary vasculature Absent GUDMAP:9746
TS23: medullary collecting duct Absent GUDMAP:9746
TS23: pelvic urothelial lining Absent GUDMAP:9746
TS23: renal vasculature Absent GUDMAP:9746
TS23: renal vesicle Ambiguous GUDMAP:9746
TS23: comma-shaped body Ambiguous GUDMAP:9746
TS23: anlage of loop of Henle of cortical renal tubule Ambiguous GUDMAP:9746 expression in distal tubule segment may extend into a portion of the anlage of loop of Henle
TS23: perihilar interstitium Ambiguous GUDMAP:9746 weak expression
TS23: cortical renal tubule of capillary loop nephron group Present GUDMAP:9746
TS23: early distal tubule of capillary loop nephron Present GUDMAP:9746
TS23: renal connecting tubule of capillary loop nephron Present GUDMAP:9746
TS23: cortical renal tubule of maturing nephron group Present GUDMAP:9746
TS23: early distal tubule of maturing nephron Present GUDMAP:9746
TS23: renal connecting tubule of maturing nephron Present GUDMAP:9746
Specimen GUDMAP:9747: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: urothelium of ureter Absent GUDMAP:9747
TS23: ureteral mesenchyme outer layer Absent GUDMAP:9747
TS23: ureter Ambiguous GUDMAP:9747
TS23: ureteral mesenchyme Ambiguous GUDMAP:9747 possible weak expression
TS23: ureteral smooth muscle layer Ambiguous GUDMAP:9747 possible weak expression
Specimen GUDMAP:9748: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Absent GUDMAP:9748
Specimen GUDMAP:9749: postnatal adult (more )
Note: This animal was sexually mature. Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: ureter Absent GUDMAP:9749
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory