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Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5540754
Gene symbol: Mfap4
Gene name: microfibrillar-associated protein 4
Probe: RIKEN clone 1110007F23 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:7556: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:7556
TS17: mesonephros Present GUDMAP:7556
TS17: nephric duct, mesonephric portion Present GUDMAP:7556
TS17: mesonephros mesenchyme Present Regionally restricted GUDMAP:7556 graded expression; weak dorsal expression and strong expression surrounding the nephric duct
TS17: nephric duct, metanephric portion Present GUDMAP:7556
TS17: metanephric mesenchyme Present GUDMAP:7556
TS17: genitourinary system mesenchyme Present GUDMAP:7556
Specimen GUDMAP:7557: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: male reproductive system Present GUDMAP:7557
TS20: mesonephros of male Present GUDMAP:7557
TS20: mesonephric mesenchyme of male Present Regionally restricted GUDMAP:7557 expression appears absent from the tissue surrounding the paramesonephric duct most notable at the rostral tip
TS20: urogenital mesentery Present GUDMAP:7557
TS20: testis Present GUDMAP:7557
TS20: coelomic epithelium of testis Present GUDMAP:7557
TS20: paramesonephric duct of male, mesonephric portion Absent GUDMAP:7557
TS20: mesonephric tubule of male Absent GUDMAP:7557
Specimen GUDMAP:7558: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7558
TS20: metanephros Present GUDMAP:7558
TS20: cap mesenchyme Present GUDMAP:7558
TS20: urogenital mesentery Present GUDMAP:7558
Specimen GUDMAP:7559: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: urinary system Present GUDMAP:7559
TS20: metanephros Present GUDMAP:7559 expression includes cap mesenchyme and possibly extends into the interstitium
TS20: cap mesenchyme Present GUDMAP:7559
TS20: urogenital mesentery Present GUDMAP:7559
TS20: primitive bladder Present GUDMAP:7559
TS20: nephrogenic interstitium Ambiguous GUDMAP:7559
TS20: renal interstitium Ambiguous GUDMAP:7559
Specimen GUDMAP:7560: embryonic day 12.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS20: female reproductive system Present GUDMAP:7560
TS20: mesonephros of female Present GUDMAP:7560
TS20: mesonephric mesenchyme of female Present Regionally restricted GUDMAP:7560 gradient of expression in mesenchyme strongest at rostral end; expression appears absent from the rostral tip surrounding the paramesonephric duct
TS20: urogenital mesentery Present GUDMAP:7560
TS20: ovary Absent GUDMAP:7560
TS20: paramesonephric duct of female, mesonephric portion Absent GUDMAP:7560
TS20: mesonephric tubule of female Absent GUDMAP:7560
Specimen GUDMAP:9952: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: genitourinary system Present GUDMAP:9952
TS17: mesonephros Present Regionally restricted GUDMAP:9952
TS17: mesonephros mesenchyme Present GUDMAP:9952
TS17: mesonephric tubule Absent GUDMAP:9952
TS17: nephric duct, mesonephric portion Ambiguous GUDMAP:9952 expression possible
TS17: metanephric mesenchyme Ambiguous GUDMAP:9952 expression uncertain
TS17: nephric duct, metanephric portion Ambiguous GUDMAP:9952 the expression in the lumen of the ureteric bud most likely to be some sort of trapping
Specimen GUDMAP:9953: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: male reproductive system Present GUDMAP:9953
TS21: mesonephros of male Present Regionally restricted GUDMAP:9953
TS21: mesonephric mesenchyme of male Present GUDMAP:9953
TS21: testis Present Regionally restricted GUDMAP:9953
TS21: interstitium of the testis Present GUDMAP:9953
TS21: mesonephric tubule of male Absent GUDMAP:9953
TS21: primary sex cord Absent GUDMAP:9953
TS21: nephric duct of male, mesonephric portion Ambiguous GUDMAP:9953 possible expression
TS21: paramesonephric duct of male, mesonephric portion Ambiguous GUDMAP:9953 possible expression
TS21: nephric duct of male, rest of Ambiguous GUDMAP:9953 expression possible
TS21: paramesonephric duct of male, rest of Ambiguous GUDMAP:9953 expression possible
TS21: developing vasculature of testis Ambiguous GUDMAP:9953 expression uncertain
Specimen GUDMAP:9954: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP. Male and female were examined; only the male is shown. Annotators reported the male expression pattern in the metanephros is identical to female.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9954
TS21: urogenital mesentery Present GUDMAP:9954
TS21: metanephros Present Regionally restricted GUDMAP:9954
TS21: cap mesenchyme Present GUDMAP:9954
TS21: ureter Present GUDMAP:9954
TS21: ureteric tip Absent GUDMAP:9954
TS21: renal interstitium Ambiguous GUDMAP:9954 expression possible
TS21: renal pelvis Ambiguous GUDMAP:9954 expression uncertain due to the fact that it was only observed on one side
Specimen GUDMAP:9955: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: urinary system Present GUDMAP:9955
TS21: ureter Present GUDMAP:9955
TS21: urogenital sinus Present Regionally restricted GUDMAP:9955
TS21: primitive bladder Present GUDMAP:9955
Specimen GUDMAP:9956: embryonic day 13.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS21: female reproductive system Present GUDMAP:9956
TS21: mesonephros of female Present Regionally restricted GUDMAP:9956
TS21: mesonephric mesenchyme of female Present GUDMAP:9956
TS21: mesovarium Present GUDMAP:9956 expression between the mesonephros and the ovary
TS21: ovary Present Regionally restricted GUDMAP:9956
TS21: mesenchymal stroma of ovary Present Regionally restricted GUDMAP:9956
TS21: mesonephric tubule of female Absent GUDMAP:9956
TS21: nephric duct of female, mesonephric portion Ambiguous GUDMAP:9956 expression possible
TS21: paramesonephric duct of female, mesonephric portion Ambiguous GUDMAP:9956 expression possible
Specimen GUDMAP:20763: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: metanephros Present GUDMAP:20763
TS23: renal cortex Present GUDMAP:20763
TS23: renal medulla Present GUDMAP:20763
TS23: renal pelvis Present GUDMAP:20763
TS23: ureter Present GUDMAP:20763
TS23: medullary collecting duct Present Spotted GUDMAP:20763
TS23: pelvic smooth muscle Present GUDMAP:20763
TS23: pelvic urothelial lining Present Spotted GUDMAP:20763
TS23: perihilar interstitium Present Regionally restricted GUDMAP:20763
TS23: urothelium of ureter Present Spotted GUDMAP:20763
TS23: ureteral mesenchyme Present GUDMAP:20763
TS23: ureteral smooth muscle layer Present Regionally restricted GUDMAP:20763
TS23: ureteral mesenchyme outer layer Present GUDMAP:20763
TS23: renal cortical vasculature Present GUDMAP:20763
TS23: renal cortical arterial system Present GUDMAP:20763
TS23: renal cortical interstitium Present Regionally restricted GUDMAP:20763
TS23: nephrogenic zone Present GUDMAP:20763
TS23: nephrogenic interstitium Present GUDMAP:20763
TS23: cap mesenchyme Present GUDMAP:20763
TS23: ureteric tip Absent GUDMAP:20763
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:20763
TS23: renal vesicle Absent GUDMAP:20763
TS23: comma-shaped body Absent GUDMAP:20763
TS23: s-shaped body Absent GUDMAP:20763
TS23: cortical renal tubule Absent GUDMAP:20763
TS23: maturing renal corpuscle Absent GUDMAP:20763
TS23: capillary loop renal corpuscle Absent GUDMAP:20763
TS23: ureteral smooth muscle layer smooth muscle component Present GUDMAP:20763
TS23: ureteral smooth muscle layer interstitium Present Regionally restricted GUDMAP:20763
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory