Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Atoh8tm3Mlkn
Name:	atonal bHLH transcription factor 8; targeted mutation 3, Mark L Kahn
MGI ID:	MGI:5532931
Synonyms:	Atoh8LacZdeltaex2
Gene:	Atoh8  Location: Chr6:72183161-72212561 bp, - strand  Genetic Position: Chr6, 32.27 cM
Alliance:	Atoh8tm3Mlkn page

Germline Transmission:	Earliest citation of germline transmission: J:203454
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: An IRES-LacZ gene trap cassette followed by an FRT flanked neo cassette and loxP site were inserted after the first three nucleotides of exon 2. RT-PCR with primers flanking exon 2 confirmed loss of transcripts in hearts of postnatal day 21 homozygous mice. (J:203454)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

32 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh8 Mutation:	7 strains or lines available

Original:	J:203454 Rawnsley DR, et al., The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40
All:	1 reference(s)