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Gene Expression Data
Assay Details
Assay
Reference: J:93820 Lillevali K, et al., Partially overlapping expression of Gata2 and Gata3 during inner ear development. Dev Dyn. 2004 Dec;231(4):775-81
Assay type: RNA in situ
MGI Accession ID: MGI:5529564
Gene symbol: Gata3
Gene name: GATA binding protein 3
Probe: Gata3 probe3
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 1B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst epithelium Present Widespread 1B Expressed all over the otic epithelium.

Specimen 1D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 1D Expressed in separate dorsal (weaker) and ventral (stronger) domains.
TS17: otocyst mesenchyme Present 1D

Specimen 1F: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: inner ear Present Regionally restricted 1F Expression was most prominent in cochlear duct and the nearby periotic mesenchyme. Only weak expression could be detected in the dorsal vestibular region. Expressed in the tip of the ventrally extending cochlear duct.
TS19: inner ear vestibular component Present Regionally restricted 1F Expression was most prominent in cochlear duct and the nearby periotic mesenchyme. Only weak expression could be detected in the dorsal vestibular region. Expressed in the tip of the ventrally extending cochlear duct.
TS19: saccule Present Regionally restricted 1F Expressed in cochlear duct and the nearby periotic mesenchyme. Expressed in the tip of the ventrally extending cochlear duct.
TS19: saccule mesenchyme Present Regionally restricted 1F Expressed in the periotic mesenchyme near cochlear duct.
TS19: endolymphatic appendage Absent 1F
TS19: saccule epithelium Absent 1F

Specimen 1H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cochlear duct Present Regionally restricted 1H Highest expression was in the medial wall.
TS20: inner ear mesenchyme Present Regionally restricted 1H Expressed in the ventral areas of the periotic mesenchyme especially adjacent to the lateral semicircular duct and the cochlear duct.
TS20: saccule epithelium Absent 1H

Specimen 2B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: inner ear vestibular component Present Regionally restricted 2B Expressed in the mesenchyme and the sensory areas of the vestibule.
TS22: vestibular component epithelium Present Regionally restricted 2B Expressed in the sensory areas of the vestibule.
TS22: cochlear duct Present Regionally restricted 2B Expressed on one side, partially overlapping with Gata2.
TS22: vestibular ganglion Present Scattered 2B

Specimen 2D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct Present Regionally restricted 2D Expressed on one side, partially overlapping with Gata2.
TS22: cochlear ganglion Present Regionally restricted 2D Expressed in broader areas, excluding the Gata2-expressing cells.

Specimen 2F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vestibular component epithelium Absent 2F

Specimen 2H: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cochlear duct Present Regionally restricted 2H Expressed on one side, partially overlapping with Gata2. Expressed in the stria vascularis.
TS26: organ of Corti Present 2H

Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 3A Expressed in the dorsal and ventral domains, overlapping with Gata2.

Specimen 3B: embryonic day 10.5; Gata2tm1Sho/Gata2tm1Sho (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 3B No change in the dorsal and ventral domains, compared with the wild-type.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: endolymphatic appendage Absent

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: endolymphatic appendage Absent
TS20: vestibular component epithelium Present Regionally restricted Expressed in the vestibular sensory patches.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vestibulo-cochlear ganglion Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory