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Gene Expression Data
Assay Details
Assay
Reference: J:88939 Rhinn M, et al., Isolation and expression of the homeobox gene Gbx1 during mouse development. Dev Dyn. 2004 Feb;229(2):334-9
Assay type: RNA in situ
MGI Accession ID: MGI:5529075
Gene symbol: Gbx1
Gene name: gastrulation brain homeobox 1
Probe: Gbx1 cDNA3
Probe preparation: Antisense RNA
Results
Specimen 2A: embryonic day 7.75 (more )
Note: headfold stage embryo
Structure Level Pattern Image Note
TS12: embryo Present Regionally restricted 2A Expression is in the posterior part.
TS12: future hindbrain Present 2A
TS12: future brain neural fold Absent 2A

Specimen 2C,E: embryonic day 8.0 (more )
Note: 4 somites, E,E' are close-ups of C, C'.
Structure Level Pattern Image Note
TS12: future hindbrain Present Regionally restricted 2C , 2E Expression corresponds to prospective rhombomere 3, 4, and 5.
TS12: future midbrain Absent 2E , 2C
TS12: midbrain-hindbrain junction Absent 2E , 2C

Specimen 2C',E': embryonic day 8.0 (more )
Note: 4 somites, E,E' are close-ups of C, C'.
Structure Level Pattern Image Note
TS12: future spinal cord neural plate Weak Regionally restricted 2E' , 2C' Expression is in the anterior neural plate.
TS12: future hindbrain Present Regionally restricted 2E' , 2C' Expression corresponds to prospective rhombomere 3, 4, and 5.

Specimen 2H: embryonic day 8.5 (more )
Note: 8 somites
Structure Level Pattern Image Note
TS13: rhombomere 3 Strong 2H
TS13: rhombomere 5 Strong 2H
TS13: future hindbrain Present Regionally restricted 2H The anterior limit of expression aligns with the preotic sulcus.
TS13: optic pit Present Regionally restricted 2H Expression is distal.
TS13: trunk Weak Regionally restricted 2H Expression is below the heart.

Specimen 2J: embryonic day 8.5 (more )
Note: 8 somites
Structure Level Pattern Image Note
TS13: rhombomere 3 Strong 2J
TS13: rhombomere 5 Strong 2J
TS13: future hindbrain Present Regionally restricted 2J The anterior limit of expression aligns with the preotic sulcus, which corresponds to rhombomere 3.
TS13: trunk Present Regionally restricted 2J Expression is below the heart.
TS13: midbrain-hindbrain junction Absent 2J

Specimen 2K: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: pericardio-peritoneal canal Present 2K
TS13: trunk Present Regionally restricted 2K Expression is below the heart.

Specimen 2K': embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: pericardio-peritoneal canal Present 2K'

Specimen 3A,C: embryonic day 9.5 (more )
Note: C,C', close-up view of the embryo shown in A.
Structure Level Pattern Image Note
TS15: rhombomere 3 Strong 3A , 3C
TS15: rhombomere 5 Strong 3A , 3C
TS15: optic vesicle Present Regionally restricted 3C , 3A Expression is in the distal part.
TS15: somite Present Regionally restricted 3A , 3C Expression is dorsal.
TS15: future spinal cord Weak Regionally restricted 3A Expression is absent in the most posterior end.
TS15: rhombomere 2 Weak 3A
TS15: rhombomere 4 Weak 3A
TS15: rhombomere 6 Weak 3A
TS15: rhombomere 7 Weak 3A
TS15: midbrain-hindbrain junction Absent 3A
TS15: otocyst Absent 3A

Specimen 3A inset: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: somite Present 3A inset

Specimen 3C': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 3 Strong 3C'
TS15: rhombomere 5 Strong 3C'
TS15: rhombomere 4 Present 3C'
TS15: rhombomere 6 Present 3C'
TS15: migrating neural crest Present Regionally restricted 3C' Expression is in neural crest migrating from rhombomere 4 and 6.

Specimen 4A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present 4A
TS17: hindbrain Present 4A
TS17: branchial arch Absent 4A
TS17: limb Absent 4A
TS17: otocyst Absent 4A

Specimen 4B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon Present Regionally restricted 4B Expression is in the medial ganglionic eminence.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 4C Expression is in the ventricular zone.

Specimen 4D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present 4D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory