Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Xkr8tm1.1Osa
Name:	X-linked Kx blood group related 8; targeted mutation 1.1, Shigekazu Nagata
MGI ID:	MGI:5528893
Gene:	Xkr8  Location: Chr4:132452208-132459857 bp, - strand  Genetic Position: Chr4, 65.81 cM
Alliance:	Xkr8tm1.1Osa page

Germline Transmission:	Earliest citation of germline transmission: J:199440
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1a

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: An FRT flanked PGK-neo cassette followed by a loxP site was inserted in intron 3 while an additional loxP site was inserted upstream of exon 3. The selection cassette was subsequently excised from properly targeted mice by flp recombinase expression. Exon 3 is thus left flanked by loxP sites. (J:199440)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Xkr8 Mutation:	17 strains or lines available

Original:	J:199440 Suzuki J, et al., Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. Science. 2013 Jul 26;341(6144):403-6
All:	2 reference(s)