Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83306
Zhang Z, et al., Malleal processus brevis is dispensable for normal hearing in mice. Dev Dyn. 2003 May;227(1):69-77
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:5528465
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Gene symbol:
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Bmp4
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Gene name:
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bone morphogenetic protein 4
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Probe:
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Bmp4 cDNA5
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
4A:
embryonic day 13.5
(more  )
Specimen
4A:
(close  )
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Genetic Background:
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CD-1
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4B:
(close )
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Genetic Background:
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involves: 129S4/SvJae * CD-1
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Mutant Allele(s):
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Msx1tm1Rilm/Msx1tm1Rilm
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: malleus pre-cartilage condensation |
Present |
Regionally restricted |
4B
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Down-regulated expression, particularly in the region where malleal manubrium develops. Unaltered expression in the lateral peripheral region of the condensing malleal primordium.
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Specimen
4C:
(close )
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Genetic Background:
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involves: 129S4/SvJae * CD-1
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Mutant Allele(s):
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Msx1tm1Rilm/Msx1tm1Rilm
Msx2tm1Rilm/Msx2tm1Rilm
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: malleus cartilage condensation |
Weak |
Regionally restricted |
4C
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Down-regulated expression in the malleal primordium. Only a residual level of expression in the lateral peripheral region.
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Specimen
not shown:
embryonic day 12.5
(more )
Specimen
not shown:
(close )
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Genetic Background:
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CD-1
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: middle ear |
Present |
Regionally restricted |
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Expressed in the developing malleal primordium.
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Analysis Tools
