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Gene Expression Data
Assay Details
Assay
Reference: J:100995 Urena JM, et al., Expression, synaptic localization, and developmental regulation of Ack1/Pyk1, a cytoplasmic tyrosine kinase highly expressed in the developing and adult brain. J Comp Neurol. 2005 Sep 19;490(2):119-32
Assay type: RNA in situ
MGI Accession ID: MGI:5526051
Gene symbol: Tnk2
Gene name: tyrosine kinase, non-receptor, 2
Probe: Ack1/Py1k cDNA2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hippocampus granule cell layer Very strong 2B
TS28: hippocampus pyramidal cell layer Very strong 2B
Specimen 2C: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer I Very strong 2C
TS28: cortical layer II Very strong 2C
TS28: cortical layer III Very strong 2C
TS28: cortical layer IV Very strong 2C
TS28: cortical layer V Very strong 2C
TS28: cortical layer VI Very strong 2C
TS28: telencephalon septum Strong Regionally restricted 2C Expression is in the lateral septal area.
TS28: caudate-putamen Strong 2C
TS28: entorhinal cortex Strong 2C
TS28: globus pallidus Strong 2C
TS28: piriform cortex Strong 2C
Specimen 2D: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cortical layer I Very strong 2D
TS28: cortical layer II Very strong 2D
TS28: cortical layer III Very strong 2D
TS28: cortical layer IV Very strong 2D
TS28: cortical layer V Very strong 2D
TS28: cortical layer VI Very strong 2D
Specimen 2E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 2E
TS28: cerebellum internal granule cell layer Weak 2E
Specimen 2F: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hindbrain Present Regionally restricted 2F Expression is in discrete nuclei.
TS28: area postrema Present 2F
TS28: hypoglossal nucleus Present 2F
Specimen 2G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: pontine reticular nucleus Present 2G
Specimen 4A,C: postnatal adult (more )
Note: Double labeled: blue - Tnk2; green - Gfap (assay MGI:5526057).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present 4A , 4C
Specimen 4D,F: postnatal adult (more )
Note: Double labeled: blue - Tnk2; green - Gfap (assay MGI:5526057).
Structure Level Pattern Image Note
TS28: dentate gyrus hilus Present 4D , 4F
Specimen 6B: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 6B Expression is in the proliferative zone.
Specimen 6C: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: hippocampus Present Regionally restricted 6C Expression is in the proliferative zone.
Specimen 6D: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: hippocampus granule cell layer Present 6D
TS28: hippocampus pyramidal cell layer Present 6D
Specimen 6F: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present 6F
TS22: telencephalon septum Present 6F
Specimen 6G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: caudate-putamen Present 6G
Specimen 6H: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: caudate-putamen Present 6H
TS28: thalamic nucleus Present 6H
Specimen 6J: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cerebellum Purkinje cell layer Present 6J
TS26: cerebellum Present Regionally restricted 6J Expression is in the external and inner granule cell layers.
Specimen 6K: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6K
TS28: cerebellum external granule cell layer Present 6K
TS28: cerebellum internal granule cell layer Present 6K
Specimen 6L: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6L
TS28: cerebellum external granule cell layer Present 6L
TS28: cerebellum internal granule cell layer Present 6L
Specimen not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Moderate
TS28: habenula Moderate
TS28: inferior colliculus Moderate
TS28: periaqueductal grey Moderate
TS28: raphe nucleus Moderate
TS28: subcommissural organ Moderate
TS28: superior colliculus Moderate
TS28: thalamic nucleus Moderate
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory