Tg(Thy1-GCaMP6s)GP4.3Dkim
Transgene Detail
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Symbol: |
Tg(Thy1-GCaMP6s)GP4.3Dkim |
Name: |
transgene insertion GP4.3, Douglas Kim |
MGI ID: |
MGI:5523977 |
Synonyms: |
GP4.3 |
Transgene: |
Tg(Thy1-GCaMP6s)GP4.3Dkim Location: unknown
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Alliance: |
Tg(Thy1-GCaMP6s)GP4.3Dkim page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: The mouse promoter drives neuron-specific expression of this transgene that includes a mutagenized green fluorescent calcium indicator (GCaMP6s), woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), and bovine growth hormone (bGH) polyadenylation sequence. GCaMP consists of a circularly permutated green fluorescent protein (cpGFP), the calcium-binding protein calmodulin
(CaM), and CaM-interacting M13 peptide. This GCaMP6s variant of GCaMP incorporates a K78H mutation in cpEGFP, as well as T381R, S383T, and R392G mutations in CaM. Line GP4.3 was generated.
(J:101977, J:203036)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
All: |
38 reference(s) |
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