Gene Expression Data
Assay Details
Assay
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Reference:
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J:69362
Koushik SV, et al., Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J. 2001 May;15(7):1209-11
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:5523261
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Gene symbol:
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Slc8a1
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Gene name:
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solute carrier family 8 (sodium/calcium exchanger), member 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
2a:
embryonic day 7.5; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2a:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2b/c:
embryonic day 8.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2b/c:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS12: heart |
Present |
|
2b
,
2c
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Specimen
2d:
embryonic day 8.5; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2d:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 8.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
2e:
embryonic day 11.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2e:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 11.0
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS18: heart |
Present |
|
2e
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Specimen
2f:
embryonic day 14.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2f:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS22: heart |
Present |
|
2f
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TS22: embryo |
Present |
Regionally restricted |
2f
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Expression was detected in the heart and several other tissues.
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Specimen
2g:
embryonic day 14.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2g:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section from whole mount
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Specimen
2h:
embryonic day 14.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2h:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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embryonic day 14.0
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Sex:
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Not Specified
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Type:
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section
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Specimen
2i:
postnatal month 3; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
2i:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1+
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Age:
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postnatal month 3
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Sex:
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Not Specified
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Type:
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whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: heart |
Present |
Uniform |
2i
|
|
TS28: lung vascular element |
Present |
Regionally restricted |
2i
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Expression was detected within the skeletal muscle of the lung arterial vessels.
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TS28: lung |
Present |
Regionally restricted |
2i
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Expression was detected within the skeletal muscle of the lung arterial vessels, but the rest of the lung does not have staining.
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Specimen
2k:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Specimen
3a +/-:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1tm1Sjc
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Age:
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embryonic day 9.0
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Sex:
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Not Specified
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Type:
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whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: heart |
Present |
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3a +/-
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Specimen
3a -/-:
embryonic day 9.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
3a -/-:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1+
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: heart |
Present |
|
3a -/-
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Expression was stronger in the null embryo because of the presence of two copies of the reporter gene.
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Specimen
3b +/-:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1tm1Sjc
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: heart |
Present |
|
3b +/-
|
|
Specimen
3b -/-:
embryonic day 9.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Specimen
3b -/-:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1+
|
Age:
|
embryonic day 9.0
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS14: heart |
Present |
|
3b -/-
|
Expression was stronger in the null embryo because of the presence of two copies of the reporter gene.
|
Specimen
3c +/-:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
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Slc8a1tm1Sjc/Slc8a1tm1Sjc
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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29 somites.
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Structure |
Level |
Pattern |
Image |
Note |
TS16: heart |
Present |
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3c +/-
|
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Specimen
3c -/-:
embryonic day 10.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Note: 29 somites.
Specimen
3c -/-:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1+
|
Age:
|
embryonic day 10.0
|
Sex:
|
Not Specified
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Type:
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whole mount
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Note:
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29 somites.
|
Structure |
Level |
Pattern |
Image |
Note |
TS16: heart |
Present |
|
3c -/-
|
|
Specimen
3e/f +/-:
(close )
Genetic Background:
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involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1tm1Sjc
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Note:
|
37 somites.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: heart |
Present |
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3f
,
3e +/-
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Specimen
3e/g -/-:
embryonic day 11.0; Slc8a1tm1Sjc/Slc8a1 +
(more )
Note: 37 somites.
Specimen
3e/g -/-:
(close )
Genetic Background:
|
involves: 129X1/SvJ * C57BL/6
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Mutant Allele(s):
|
Slc8a1tm1Sjc/Slc8a1+
|
Age:
|
embryonic day 11.0
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Note:
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37 somites.
|
Structure |
Level |
Pattern |
Image |
Note |
TS18: heart |
Present |
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3g
,
3e -/-
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