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Gene Expression Data
Assay Details
Assay
Reference: J:78716 Lopez-Bendito G, et al., Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J Comp Neurol. 2002 Sep 16;451(2):153-69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5521788
Gene symbol: L1cam
Gene name: L1 cell adhesion molecule
Antibody: Anti-L1
Results
Specimen 9A,9C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral internal capsule Present Regionally restricted 9A Immunoreactive projections extended from the dorsal thalamus, through the internal capsule, toward the cortex and terminated in the intermediate zone.
TS23: thalamus Present Regionally restricted 9A Immunoreactive projections extended from the dorsal thalamus, through the internal capsule, toward the cortex and terminated in the intermediate zone.
TS23: cerebral cortex Present Regionally restricted 9C , 9A Immunoreactive projections extended from the dorsal thalamus, through the internal capsule, toward the cortex and terminated in the intermediate zone.
TS23: cerebral cortex intermediate zone Present Regionally restricted 9C , 9A Immunoreactive projections extended from the dorsal thalamus, through the internal capsule, toward the cortex and terminated in the intermediate zone.

Specimen 9B,9D: embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: diencephalon Present Regionally restricted 9B Immunopositive fibers extend from the diencephalon toward the ventral surface of the pallidum. The bundle connects the dorsal thalamus and the basal-marginal telencephalon and was not detected in wild type.
TS23: pallidum Present Regionally restricted 9B Immunopositive fibers extend from the diencephalon toward the ventral surface of the pallidum. The bundle connects the dorsal thalamus and the basal-marginal telencephalon and was not detected in wild type.
TS23: telencephalon Present Regionally restricted 9B Immunopositive fibers extend from the diencephalon toward the ventral surface of the pallidum. The bundle connects the dorsal thalamus and the basal-marginal telencephalon and was not detected in wild type.
TS23: thalamus Present Regionally restricted 9B Immunopositive fibers extend from the diencephalon toward the ventral surface of the pallidum. The bundle connects the dorsal thalamus and the basal-marginal telencephalon and was not detected in wild type.
TS23: cerebral cortex intermediate zone Weak Regionally restricted 9B , 9D Only a few thalamic fibers were detected in the cortical intermediate zone in the mutant.

Specimen 10A,10C,10E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral internal capsule Present Regionally restricted 10A , 10C Immunoreactive thalamic fibers traveled within the internal capsule.
TS25: thalamus Present Regionally restricted 10A , 10C Immunoreactive thalamic fibers traveled within the internal capsule.
TS25: cerebral cortex Present 10E , 10A

Specimen 10B,10D,10F: embryonic day 17.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS25: diencephalon Present Regionally restricted 10B , 10D Immunoreactive thalamic fibers deviated ventrally at the boundary between the diencephalon and telencephalon in the mutant.
TS25: telencephalon Present Regionally restricted 10B , 10D Immunoreactive thalamic fibers deviated ventrally at the boundary between the diencephalon and telencephalon in the mutant.
TS25: thalamus Present Regionally restricted 10B , 10D Immunoreactive thalamic fibers deviated ventrally at the boundary between the diencephalon and telencephalon in the mutant.
TS25: cerebral cortex Present 10B , 10F Immunoreactive thalamic fibers reach the cortex in the mutant, despite the differing routes of the axons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory