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Gene Expression Data
Assay Details
Assay
Reference: J:78716 Lopez-Bendito G, et al., Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J Comp Neurol. 2002 Sep 16;451(2):153-69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5521605
Gene symbol: Cntn2
Gene name: contactin 2
Results
Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex intermediate zone Present 3D
TS21: cerebral cortex Present Regionally restricted 3D Expression was detected in corticofugal fibers projecting toward the striatocortical junction.

Specimen 3E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex intermediate zone Present 3E
TS21: cerebral cortex Present Regionally restricted 3E Expression was detected in corticofugal fibers projecting toward the striatocortical junction.

Specimen 3J: embryonic day 13.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 3J Immunoreactivity in corticofugal fibers was located closer to the pial surface in mutants. The front of staining extended to similar regions of the striatocortical junction and was more widespread as it reached the lateral part of the internal capsule.

Specimen 3K: embryonic day 13.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS21: cerebral cortex Present Regionally restricted 3K Immunoreactivity in corticofugal fibers was located closer to the pial surface in mutants. The front of staining extended to similar regions of the striatocortical junction and was more widespread as it reached the lateral part of the internal capsule.

Specimen 11A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 11A Expression was detected in corticofugal fibers projecting toward the striatocortical junction.

Specimen 11B: embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 11B Expression was detected in corticofugal fibers projecting toward the striatocortical junction similar to wild type.

Specimen 11C,11G,11K: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present Regionally restricted 11C , 11G Expression was detected in corticofugal fibers projecting toward the striatocortical junction.
TS25: cerebral cortex intermediate zone Present 11C , 11K
TS25: cerebral cortex marginal zone Present 11C , 11K
TS25: cortical plate Present 11C , 11K
TS25: cortical subplate Present 11C , 11K

Specimen 11D,11H,11L: embryonic day 17.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS25: cerebral cortex Present Regionally restricted 11H , 11D Expression was detected in corticofugal fibers projecting toward the striatocortical junction similar to wild type. There were no apparent changes in the trajectory of the fibers.
TS25: cerebral cortex intermediate zone Present 11D , 11L
TS25: cortical subplate Present 11D , 11L
TS25: cerebral cortex marginal zone Weak 11L , 11D Expression was significantly reduced in the the mutant compared to wild type.
TS25: cortical plate Weak 11L , 11D Expression was significantly reduced in the the mutant compared to wild type.

Specimen 11E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 11E Expression was detected in corticofugal fibers projecting toward the striatocortical junction.
TS23: cerebral cortex intermediate zone Present 11E
TS23: cerebral cortex marginal layer Present 11E
TS23: cortical plate Present 11E
TS23: cortical subplate Present 11E

Specimen 11F: embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: cerebral cortex Present Regionally restricted 11F Expression was detected in corticofugal fibers projecting toward the striatocortical junction similar to wild type.
TS23: cerebral cortex intermediate zone Present 11F
TS23: cortical subplate Present 11F
TS23: cerebral cortex marginal layer Weak 11F Expression was significantly reduced in the the mutant compared to wild type.
TS23: cortical plate Weak 11F Expression was significantly reduced in the the mutant compared to wild type.

Specimen 11I: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 11I
TS23: cerebral cortex marginal layer Present 11I
TS23: cortical plate Present 11I
TS23: cortical subplate Present 11I

Specimen 11J: embryonic day 15.5; Emx2tm1Pgr/Emx2tm1Pgr (more )
Structure Level Pattern Image Note
TS23: cerebral cortex intermediate zone Present 11J
TS23: cortical subplate Present 11J
TS23: cerebral cortex marginal layer Weak 11J Expression was significantly reduced in the the mutant compared to wild type.
TS23: cortical plate Weak 11J Expression was significantly reduced in the the mutant compared to wild type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory