Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Pmch-cre)1Rck
Name:	transgene insertion 1, Jeffrey M Friedman
MGI ID:	MGI:5521470
Synonyms:	Pmch-cre, Tg(Pmch-cre)
Transgene:	Tg(Pmch-cre)1Rck  Location: unknown
Alliance:	Tg(Pmch-cre)1Rck page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pmch-cre)1Rck expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Pmch (MGI:97629)   Mutation details: Bacterial artificial chromosome (BAC) library (CHORI) was used to identify a BAC (#RP23-129A21) containing the entire mouse pro-melanin-concentrating hormone (Pmch) gene. This BAC was generated to contain a cre coding sequence downstream from the start codon, and was microinjected into fertilized C57BL/6J oocytes. (J:202805)

Activity:	Tissue activity of this recombinase allele
Driver:	Pmch (mouse) Summary of all recombinase alleles driven by Pmch. Alliance mouse Pmch gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:202805 Jego S, et al., Optogenetic identification of a rapid eye movement sleep modulatory circuit in the hypothalamus. Nat Neurosci. 2013 Nov;16(11):1637-43
All:	3 reference(s)